From the Research
Melatonin is likely safe during pregnancy, according to the most recent and highest quality study, and may even have beneficial effects on fetal development and placental health. The study published in 2022 1 found that melatonin use during pregnancy and breastfeeding is probably safe in humans, with no major safety concerns or adverse events reported. This study is the most recent and of high quality, and its findings should be prioritized over earlier studies.
Key Points
- Melatonin has been shown to have antioxidant and anti-inflammatory effects, which can help maintain a stable environment for both the mother and the fetus 2.
- The placenta synthesizes its own melatonin, which plays a crucial role in regulating immune homeostasis during pregnancy 2.
- While earlier studies suggested caution with melatonin use during pregnancy, the most recent evidence suggests that it is likely safe 1.
- Natural methods to improve sleep, such as maintaining a consistent sleep schedule and practicing relaxation techniques, are still preferred during pregnancy.
- If sleep problems are severe, consulting with a healthcare provider is recommended to discuss the potential benefits and risks of melatonin supplementation.
Benefits of Melatonin During Pregnancy
- May help reduce oxidative stress and inflammation in the placenta 2.
- Can help regulate immune homeostasis during pregnancy 2.
- May have beneficial effects on fetal development and placental health 3, 4, 5.
Precautions
- While melatonin is likely safe, it is still important to consult with a healthcare provider before taking any supplements during pregnancy.
- The effects of supplemental doses of melatonin on fetal development are not fully understood, and more research is needed to confirm its safety and efficacy.