What is the treatment for a spider bite?

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Treatment for Spider Bites

The treatment for spider bites should include thorough wound irrigation with copious amounts of clean water, application of ice for pain relief (with a barrier between ice and skin), and over-the-counter pain medications, while avoiding suction or tourniquets. 1, 2

Initial Assessment and First Aid

  • Thoroughly irrigate the bite wound with copious amounts of clean water to reduce venom load and prevent infection 1, 2
  • Remove rings and other constricting objects from the bitten extremity as swelling may occur 2
  • Apply ice to the bite site for pain relief, but place a thin barrier between the ice and skin to prevent tissue damage 1, 2
  • Do not apply suction to the bite site as this is ineffective and potentially harmful 1, 2
  • Do not apply tourniquets or pressure immobilization bandages as these may worsen tissue injury 2

Medical Management Based on Spider Type

Brown Recluse Spider Bites

  • For brown recluse spider bites, which can cause dermonecrosis within 72-96 hours, treatment should include rest, ice compresses, and antibiotics 3
  • Dapsone may be beneficial for controlling brown recluse necrotic lesions 3, 4
  • Delay surgical intervention for several weeks to allow demarcation of necrotic tissue 3
  • Systemic corticosteroids may be helpful in treating rare systemic loxoscelism, which presents with minimal skin changes but massive hemolysis 3

Black Widow Spider Bites

  • Black widow bites primarily produce muscle cramping, pain, and neuromuscular symptoms rather than marked skin changes 3
  • Treatment includes pain control, muscle relaxants, and calcium gluconate 3, 5, 4
  • Specific black widow antivenin is available but should be reserved for severe reactions 5, 4
  • Intravenous fluids may be sufficient for mild to moderate cases 6

When to Seek Medical Attention

  • Seek immediate medical attention if systemic symptoms develop, including difficulty breathing, muscle rigidity, dizziness, or confusion 7, 2
  • Medical care should be sought if pain extends beyond the bite site, becomes severe, is not controlled by over-the-counter pain medications, or if an open wound develops 7
  • Hospitalization may be necessary if lesions enlarge rapidly or there are signs of systemic poisoning 5

Pain Management

  • Over-the-counter acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) are recommended for pain relief 7, 2
  • For more severe pain, prescription analgesics may be necessary 5
  • Topical lidocaine (5%) can be applied if the skin is intact to provide significant pain reduction 7

Common Pitfalls to Avoid

  • Do not assume antibiotics are needed for swelling around the bite site, as swelling is typically caused by mediator release, not infection 7
  • Avoid routine prophylactic antibiotics unless signs of infection are present 7
  • Do not attempt to identify the spider yourself - many spider bites are misdiagnosed because the spider is not seen at the time of the bite 8
  • Do not delay seeking medical attention if symptoms worsen or systemic effects develop 7, 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Treatment for Brown Recluse Spider Bites

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Spiders and spider bites.

Dermatologic clinics, 1990

Research

Managing arthropod bites and stings.

The Physician and sportsmedicine, 1998

Research

[Spider bite in a child].

Harefuah, 1989

Guideline

Treatment for Scorpion Stings

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Spider bites.

The Journal of the American Board of Family Practice, 1995

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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