Differential Diagnosis for a 19-year-old Female with a Painful Lump in the Left Labia/Groin

Single Most Likely Diagnosis

• Bartholin's cyst: Given the family history of Bartholin's cyst and the presentation of a painful lump in the labia, this is the most likely diagnosis. Bartholin's cysts are common in women of reproductive age and can cause a painful lump in the labia.

Other Likely Diagnoses

• Ingrown hair or folliculitis: These conditions can cause a painful lump in the groin area and are common in young women.
• Sebaceous cyst: A sebaceous cyst can cause a painful lump in the labia or groin area and is a common benign condition.
• Vulvar abscess: Although less likely given the lack of redness, a vulvar abscess can cause a painful lump in the labia and should be considered.

Do Not Miss Diagnoses

• Malignancy (e.g., vulvar cancer): Although rare in young women, malignancy should not be missed as it can have severe consequences if not treated promptly.
• Tuberculosis or other granulomatous infections: These infections can cause chronic painful lumps in the groin area and have significant implications for treatment and public health.
• Hidradenitis suppurativa: This condition can cause painful lumps in the groin area and has significant implications for treatment and quality of life.

Rare Diagnoses

• Dermoid cyst: A dermoid cyst is a rare benign tumor that can cause a painful lump in the labia or groin area.
• Vulvar endometriosis: Endometriosis can cause painful lumps in the vulvar area, although this is a rare presentation.
• Lipoma: A lipoma is a rare benign tumor that can cause a painful lump in the labia or groin area.