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Differential Diagnosis for Crusted Vesicles on Forehead

  • Single most likely diagnosis
    • Impetigo: This is a highly contagious bacterial skin infection that often presents with crusted vesicles or pustules, commonly on the face, including the forehead. It's caused by Staphylococcus aureus or Streptococcus pyogenes.
  • Other Likely diagnoses
    • Herpes simplex virus (HSV) infection: Although more commonly associated with oral or genital areas, HSV can cause lesions on the forehead, especially if there's a history of similar outbreaks or exposure.
    • Contact dermatitis: An allergic reaction or irritant contact dermatitis could lead to vesicular lesions on the forehead, especially if the individual has been exposed to new skincare products, makeup, or other potential allergens.
    • Eczema (atopic dermatitis): This chronic condition can cause dry, itchy skin and sometimes vesicles, particularly in individuals with a history of atopic diseases.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Varicella-zoster virus (VZV) reactivation (shingles): Although less common on the forehead, shingles can present with a vesicular rash and is important to diagnose due to the potential for serious complications, such as postherpetic neuralgia or ocular involvement if the rash affects the area around the eye.
    • Meningococcemia: This severe infection can cause a petechial or vesicular rash and is a medical emergency. Early recognition and treatment are crucial to prevent high mortality.
  • Rare diagnoses
    • Pemphigus vulgaris: An autoimmune disease that can cause blistering of the skin and mucous membranes. It's rare but important to consider due to its potential severity and need for specific treatment.
    • Bullous pemphigoid: Another autoimmune blistering disease that, although rare, could present with vesicles on the forehead among other areas of the body.
    • Dermatitis herpetiformis: A skin manifestation of celiac disease, characterized by intensely itchy, blistering skin. It's less common but should be considered, especially if there are gastrointestinal symptoms or a family history of celiac disease.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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