Differential Diagnosis for Post-Venofer Injection Symptoms

Given the symptoms of wobbly legs, general heavy feeling, brain fog, and lightheadedness after Venofer (iron sucrose) injections, the following differential diagnoses are considered:

• Single Most Likely Diagnosis
  • Iron overload or acute iron intoxication: This is a common side effect of iron sucrose injections, especially if the dose is too high or if the patient has a history of iron overload. Symptoms can include dizziness, headache, and nausea, which align with the described symptoms.
• Other Likely Diagnoses
  • Hypotension: Iron sucrose can cause a decrease in blood pressure, leading to dizziness and lightheadedness.
  • Allergic reaction: Although rare, an allergic reaction to Venofer can cause a range of symptoms, including dizziness, nausea, and a general feeling of being unwell.
  • Anaphylaxis: A severe, life-threatening allergic reaction that requires immediate medical attention.
• Do Not Miss Diagnoses
  • Anaphylactic shock: A severe, life-threatening condition that requires immediate medical attention. Symptoms can include dizziness, fainting, and a feeling of impending doom.
  • Septic shock: Although unlikely, if the injection site becomes infected, it can lead to septic shock, a life-threatening condition.
• Rare Diagnoses
  • Iron-induced neuropathy: A rare condition where iron deposits can cause nerve damage, leading to symptoms such as numbness, tingling, and weakness in the legs.
  • Hypersensitivity pneumonitis: A rare condition where the lungs become inflamed due to an allergic reaction, which can cause symptoms such as shortness of breath and coughing.

It is essential to consult a healthcare professional for proper evaluation and management of these symptoms, as some of these conditions can be life-threatening if left untreated.