Treatment of Friction Blisters
For friction blisters, the recommended treatment is to leave blisters intact when possible, but when they are large or in functionally problematic areas, pierce them with a sterile needle to drain the fluid while preserving the blister roof as a natural protective covering. 1, 2
Initial Management
- Blisters should generally be left intact whenever possible as this helps prevent secondary bacterial infection 1, 2
- For large blisters or those in functionally problematic areas (such as the sole of the foot), pierce the blister with a sterile needle to release fluid while preserving the blister roof 1, 2
- When draining a blister, select a site that allows drainage by gravity and keep the bisel of the needle facing upward 2
- Apply gentle pressure with sterile gauze to facilitate drainage and absorb fluid 2
- Do not remove the blister roof as it serves as a natural biological dressing 1, 2
Wound Care After Drainage
- Clean the area gently with an antimicrobial solution 2
- Apply a mild emollient such as 50% white petroleum and 50% liquid paraffin to support the skin barrier function 2
- Cover painful eroded areas with a low-adhesion dressing held in place with soft elasticated viscose 1
- For extensive erosions, consider antiseptic baths or soaks with potassium permanganate or antiseptic-containing bath oils to dry the lesions and prevent infection 1
Prevention of Infection
- Monitor for signs of infection, as this is a significant risk with open blisters 2
- Perform daily cleansing with antibacterial products to reduce colonization 2
- Change dressings using aseptic technique 2
- If clinical signs of infection appear, obtain bacterial and viral cultures from the erosions 2
- Apply topical antimicrobials for short periods when appropriate 2
Prevention of Friction Blisters
- Wear properly fitting shoes that are broken in gradually 3, 4
- Consider doubling up on socks to reduce friction 4
- Apply protective padding over potential blister formation sites 3, 4
- Use drying foot powders and non-slip insoles 3
- Apply lubricants judiciously to reduce friction 5, 4
- Address any underlying biomechanical foot defects that may predispose to blister formation 3
Follow-up Considerations
- For blisters covering less than 10% of body surface area that are asymptomatic, observation and local wound care may be sufficient 2
- Document the number and location of blisters daily to monitor disease progression 2
- Consider adhesive tape rather than wide area fixation dressing for treatment, as it has been associated with better healing outcomes and higher satisfaction 6