What is the treatment for an infected Bartholin (Bartholin's) cyst?

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Treatment of Infected Bartholin Cysts

For infected Bartholin cysts (Bartholin gland abscesses), incision and drainage with placement of a Word catheter or similar drainage device is the recommended first-line treatment, followed by oral antibiotics to treat the infection.

Diagnosis and Assessment

  • Bartholin gland cysts account for approximately 2% of all gynecologic visits per year 1
  • An infected Bartholin cyst (abscess) typically presents with significant pain, swelling, and tenderness at the posterior portion of the labia majora 2
  • Infected cysts larger than 2 cm should be drained as they do not tend to resolve spontaneously and have high risk of recurrence 3

Treatment Options

First-line Treatment: Drainage Procedures

  • Incision and drainage with Word catheter placement is the most frequently employed technique for office and emergency department management 4
  • The Word catheter is inserted into the cyst or abscess cavity after making a small incision, then inflated with 2-3 mL of water or saline to keep it in place 2
  • The catheter should remain in place for 4-6 weeks to allow epithelialization of the drainage tract 4
  • Alternative drainage techniques include:
    • Placement of a loop of plastic tubing if a Word catheter is unavailable 4
    • Marsupialization (creating a permanent opening by suturing the cyst wall to the surrounding tissue) 2

Antibiotic Therapy

  • After drainage, oral antibiotics should be prescribed to treat the infection 4
  • Common pathogens include skin flora and polymicrobial infections 5
  • Appropriate antibiotic options include:
    • Amoxicillin-clavulanate (500/875 mg twice per day) as first-line therapy 5
    • Alternatives for penicillin-allergic patients include:
      • Doxycycline (100 mg twice per day) 5
      • Clindamycin (300 mg three times per day) 5
  • Duration of antibiotic therapy is typically 5-9 days 5

Special Considerations

  • Be aware that some Bartholin gland abscesses may be caused by resistant organisms:
    • Cases of penicillin-resistant Streptococcus pneumoniae (PRSP) and beta-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae (BLNAR) have been reported 6
    • For suspected resistant organisms, consider cephalosporins like cefteram pivoxil 6
  • For recurrent infections, more definitive surgical options may be considered:
    • Complete surgical excision of the Bartholin gland 1
    • Carbon dioxide laser treatment 1
    • Silver nitrate application 1

Follow-up Care

  • Patients should be seen for follow-up in 2-3 weeks to ensure proper healing 4
  • The drainage device (Word catheter or tubing) can be removed after epithelialization of the drainage tract, typically after 4-6 weeks 4
  • Patients should be instructed to return sooner if symptoms worsen or if the catheter falls out prematurely 2

Common Pitfalls to Avoid

  • Simple lancing without catheter placement often leads to recurrence and should be avoided 2
  • Failure to provide adequate analgesia before the procedure can make it difficult to perform properly 2
  • In women over 40, consider the possibility of malignancy in cases of persistent or recurrent Bartholin gland enlargement 1
  • Inadequate antibiotic coverage may lead to treatment failure, especially with resistant organisms 6

References

Research

The bartholin gland cyst: past, present, and future.

Journal of lower genital tract disease, 2004

Research

Office management of Bartholin gland cysts and abscesses.

American family physician, 1998

Research

Management of Bartholin Duct Cysts and Gland Abscesses.

Journal of midwifery & women's health, 2019

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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