What does a physical examination for epididymitis (inflammation of the epididymis) entail?

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Last updated: March 26, 2025View editorial policy

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From the Guidelines

A physical examination for epididymitis entails a comprehensive assessment including examination of the penis, measurement and palpation of the testes, checking for the presence and consistency of the vasa and epididymides, and a digital rectal examination. The examination should begin with a visual inspection of the scrotum for redness and swelling, followed by careful palpation to assess tenderness, swelling, and whether the epididymis feels distinct from the testicle 1. The examiner should also perform a prehn sign test and check for a cremasteric reflex. Additional components may include checking for discharge from the penis and examining the abdomen for tenderness. Some key points to consider during the physical examination include:

  • Examination of the penis, including the location of the urethral meatus
  • Measurement and palpation of the testes
  • Checking for the presence and consistency of the vasa and epididymides
  • Checking for the presence of a varicocele
  • Body habitus and secondary sex characteristics, including hair distribution and breast development
  • A digital rectal examination 1. It is also important to consider the patient's age and sexual history, as epididymitis can be caused by different organisms in different populations 1.

From the Research

Physical Examination for Epididymitis

A physical examination for epididymitis entails several key components, including:

  • Inspection of the scrotum for swelling and redness
  • Palpation of the epididymis to assess for tenderness and swelling
  • Evaluation of the testis to determine if it is in an anatomically normal position 2
  • Assessment for urinary symptoms such as dysuria and urinary frequency 2

Key Findings

Key findings on physical examination may include:

  • A swollen and tender epididymis 2
  • The testis in an anatomically normal position 2
  • Presence of posterior scrotal pain 2
  • Urinary symptoms such as dysuria and urinary frequency 2

Diagnostic Considerations

In addition to physical examination, diagnostic considerations may include:

  • Laboratory tests such as urine analysis and culture to evaluate for infection 3
  • Imaging studies such as ultrasonography or radionuclide scan to evaluate the scrotum and epididymis 3, 4
  • Evaluation of acute-phase proteins such as C-reactive protein to differentiate epididymitis from noninflammatory conditions 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Epididymitis: An Overview.

American family physician, 2016

Research

Acute epididymitis in boys: are antibiotics indicated?

British journal of urology, 1997

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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