What are the basic guidelines for managing common internal medicine conditions?

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Last updated: October 25, 2025View editorial policy

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Basic Guidelines for Managing Common Internal Medicine Conditions

The management of common internal medicine conditions should follow a patient-centered approach that addresses multimorbidity and polypharmacy through systematic assessment, shared decision-making, individualized treatment plans, and structured follow-up to optimize outcomes and quality of life. 1

Identification of Patients Requiring Comprehensive Management

  • Identify patients with multimorbidity at risk of adverse events (e.g., unplanned hospital admission) using prognostic models either opportunistically during routine care or through systematic screening 1
  • Pay particular attention to patients with multiple conditions who take multiple medications (polypharmacy), as they face increased complexity in care management 1
  • Consider patients with chronic multisymptom illness (CMI) who may present with multiple poorly understood symptoms across different body systems 1

Comprehensive Assessment

Medical History and Clinical Evaluation

  • Conduct thorough assessment of interacting conditions and treatments, including complete medical history and clinical evaluation 1
  • Document all known diagnoses, conditions, existing laboratory results, and medication-related problems in the electronic medical record 2
  • Assess physiological and functional status, including nutritional and hydration requirements 2
  • Evaluate for common comorbidities such as chronic pain, depression, and anxiety 2

Medication Review

  • Create an accurate medication list including all prescriptions, over-the-counter medications, supplements, and herbal remedies 2
  • Use validated tools like Beers Criteria or STOPP/START to identify potentially inappropriate medications in older adults 2
  • Evaluate potential drug-drug interactions using interaction databases, with particular attention to QT prolongation risks, anticoagulant interactions, and serotonin syndrome potential 2
  • Identify medications that may worsen existing conditions (drug-disease interactions), such as NSAIDs in heart failure, chronic kidney disease, or hypertension 2

Patient Preferences and Goal Setting

  • Elicit patient preferences and expectations regarding their care 1
  • Engage in shared decision-making with patients about treatment options and level of involvement 1
  • Discuss with patients the purpose of medication optimization to improve quality of life and function 2
  • Encourage patients to express their personal values, aims, and priorities regarding treatment 2

Individualized Management

Treatment Optimization

  • Apply guiding principles that optimize treatment benefits over possible harms 1
  • Consider cognitive-behavioral therapy and mindfulness-based treatments for patients with chronic multisymptom illness 1
  • Consider exercise for patients with symptoms consistent with fibromyalgia syndrome 1
  • Target medications from which patients no longer derive reasonable benefit for potential deprescribing 2
  • Consider deprescribing when potential harm outweighs benefit, including education about risks for patients and families 2

Care Planning and Communication

  • Develop care plans that address ongoing medical and social care needs while focusing on enhancing social connectedness and community involvement 1
  • Use an individualized patient-held medication plan that includes specific information on drugs and instructions for usage 1
  • Ensure ongoing and adequate communication, particularly around medicines and wider care plans 1
  • Document practice guidelines clearly, including standardized referral data, diagnosis protocols, baseline assessments, and therapeutic algorithms 1

Monitoring and Follow-up

  • Review and update medication/care plans regularly to recognize and record changes in needs 1
  • Schedule regular follow-up appointments to assess medication effectiveness and adverse effects 2
  • Monitor treatment effects and clinical parameters, as well as side effects at follow-up appointments 1
  • Increase monitoring frequency during care transitions (hospital admission, transfers between wards, discharge) 2
  • Consider using an individualized patient-held medication plan for self-management support 1
  • Review the self-management plan to ensure the person does not have problems using it 1

Organizational Considerations

  • Implement a multidisciplinary team approach, especially involving clinical pharmacists when available 2
  • Consider using computerized decision support systems that support decision making and prescribing but do not replace clinical judgment 1
  • Conduct regular self-assessment of the unit to improve quality of care and service 1
  • Implement systems to capture and respond to patient feedback on their experience 1
  • Keep thorough and accurate electronic patient records adapted to the specific care unit 1

Common Pitfalls and How to Avoid Them

  • Avoid applying individual disease-oriented guidelines to patients with multimorbidity without consideration of interactions between diseases and treatments 1
  • Be aware that newly introduced medications may not have reached steady state at discharge due to short hospital stays, requiring careful monitoring after discharge 1
  • Recognize that cognitive dysfunction is frequently underdiagnosed in patients with multimorbidity and polypharmacy but has major impact on health status 1
  • Avoid prescribing cascades where additional medications are prescribed to counteract side effects of other medications 1
  • Remember that good guidelines are not cookbooks; they augment but do not replace clinical judgment 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Managing Polypharmacy in Non-Communicable Disease Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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