What percentage of patients who undergo Anterior Cruciate Ligament (ACL) reconstruction and meniscus repair later require Total Knee Arthroplasty (TKA)?

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Percentage of ACL Reconstruction and Meniscus Repair Patients Requiring Total Knee Arthroplasty

Patients who undergo ACL reconstruction with meniscus repair have an extremely low rate (approximately 0.01%) of subsequently requiring total knee arthroplasty (TKA). 1

Risk Factors and Conversion Rates

  • ACL reconstruction with meniscus repair has the lowest rate of subsequent TKA (0.01%) among common sports medicine procedures of the knee 1
  • ACL reconstruction alone (without meniscus repair) has a similarly low rate of conversion to TKA with an odds ratio of 0.17 compared to other knee procedures 1
  • Patients who undergo ACL reconstruction with meniscus repair have the longest period from index procedure to TKA at approximately 2,827 days (7.7 years) 1

Impact of Meniscus Status

  • The status of the meniscus at the time of ACL reconstruction is a strong predictor of the risk of osteoarthritis and subsequent need for TKA 2
  • Patients who undergo total meniscectomy are at 2- to 10-fold increased risk of developing osteoarthritis relative to those with intact menisci 2
  • Partial meniscectomy carries a more than 6-fold increased risk of TKA compared with isolated ACL reconstruction 3
  • ACL reconstruction with medial meniscectomy increases osteoarthritis odds 3.14 times compared with ACL reconstruction alone 4
  • ACL reconstruction with partial meniscectomy increases osteoarthritis odds 1.87 times compared with ACL reconstruction alone 4

Long-Term Outcomes

  • Long-term TKA failure rates are generally <1% per year for the general TKA population 4
  • The prevalence of osteoarthritis in ACL-deficient knees is about 40% after 15 years and close to 90% after 25 to 35 years 2
  • 94% of patients who underwent ACL reconstruction had stable knees after 15-20 years and significantly lower percentage of osteoarthritis compared to conservatively treated patients 5

Risk Factors for Meniscus Repair Failure

  • The failure rate of repaired medial meniscus is approximately 10.0% and lateral meniscus is 7.1% 6
  • Risk factors for subsequent meniscal surgery after ACL reconstruction include:
    • Presence of medial meniscus injury at the time of ACL reconstruction
    • Increased anterior tibial translation post-surgery
    • Longer follow-up period after ACL reconstruction 6

Clinical Implications

  • Meniscus preservation during ACL reconstruction is critical for long-term knee health and minimizing the risk of requiring TKA 1, 3
  • Cartilage injury at the time of ACL reconstruction increases osteoarthritis odds 2.31 times compared with either no or less severe injury 4
  • Salvage interventions such as meniscus transplantation have the highest risk of conversion to TKA (odds ratio = 3.06) 1

Common Pitfalls and Caveats

  • Identifying the cause of a painful knee after ACL reconstruction is critical before considering revision surgery, as "reoperation is unwise and frequently associated with suboptimal results" in cases of unexplained pain 4
  • The all-inside technique for medial meniscus repair has shown a significantly higher failure rate compared to other repair techniques or partial resection 6
  • Patients showing early evidence of arthritis at short- to medium-term follow-up after ACL reconstruction are at high risk for progression over subsequent years 2

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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