What is the diagnosis for a 19-year-old female (19f) presenting with pharyngitis, cough, and hyperpyrexia (fever of 104 degrees Fahrenheit)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 26, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for a 19-year-old female with sore throat, cough, and fever of 104

  • Single most likely diagnosis
    • Viral pharyngitis: This is the most common cause of sore throat and fever in young adults, and the presence of a cough suggests a viral upper respiratory infection.
  • Other Likely diagnoses
    • Influenza: The high fever and cough are consistent with influenza, especially during flu season.
    • Streptococcal pharyngitis: Although less common than viral pharyngitis, strep throat is a significant consideration in young adults with sore throat and fever.
    • Acute bronchitis: The cough and fever could be indicative of an acute bronchitis, which is often caused by a viral infection.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Epiglottitis: Although rare, epiglottitis is a life-threatening condition that requires prompt recognition and treatment.
    • Pneumonia: Bacterial pneumonia can present with high fever, cough, and sore throat, and is a potentially life-threatening condition if not treated promptly.
    • Lemierre's syndrome: This rare condition is characterized by a bacterial infection of the throat, followed by sepsis and thrombophlebitis, and can be fatal if not recognized and treated.
  • Rare diagnoses
    • Mononucleosis: Although more common in young adults, mononucleosis (caused by Epstein-Barr virus) can present with sore throat, fever, and cough, but is less likely than other viral infections.
    • Tuberculosis: Although rare in young adults, TB can present with chronic cough, fever, and sore throat, and should be considered in patients with risk factors or exposure history.
    • Kawasaki disease: This rare condition can present with fever, sore throat, and cough, but is more commonly seen in children under the age of 5.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.