What is the initial workup for a 20-month-old presenting to the emergency department (ED) with crying?

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Initial Workup for a 20-Month-Old Presenting to the Emergency Department with Crying

The initial workup for a 20-month-old presenting to the emergency department with crying should focus on a thorough physical examination to identify potential serious causes, as approximately 61% of cases of acute, unexplained excessive crying in infants may have serious underlying etiologies. 1

Initial Assessment

  • First verify scene safety and check for responsiveness of the child 2
  • Assess airway, breathing, and circulation, checking pulse and breathing simultaneously 2
  • If the child is responsive, breathing normally, and has a normal pulse, continue with detailed assessment 2
  • Monitor vital signs including heart rate, respiratory rate, temperature, and oxygen saturation 2

History Taking

  • Obtain detailed history about the onset, duration, and pattern of crying 1, 3
  • Ask about associated symptoms such as fever, vomiting, diarrhea, or recent illness 1
  • Inquire about feeding patterns, sleep patterns, and any recent changes 3
  • Document any recent trauma, falls, or injuries 1
  • Ask about medication use and potential exposures to toxins 1
  • Review past medical history and family history 1

Physical Examination

  • Conduct a comprehensive physical examination, which should include:
    • Careful skin inspection underneath all clothing (looking for rashes, bruises, or signs of trauma) 1, 4
    • Palpation of all large bones to detect fractures 1, 4
    • Fluorescein staining of the cornea to identify corneal abrasions 1, 4
    • Eversion of eyelids to check for foreign bodies 1, 4
    • Rectal examination to check for fissures or blood 1, 4
    • Retinal examination to rule out retinal hemorrhages 1, 4
    • Thorough neurological examination 1, 4
    • Examination of ears, throat, and abdomen 1, 4
    • Assessment for signs of increased intracranial pressure 1
    • Check for facial petechiae, which are rare with crying alone and may indicate trauma 5

Laboratory and Diagnostic Testing

  • Urinalysis and urine culture are recommended, especially for infants under 4 months of age, as urinary tract infections are among the most common serious causes of crying 1, 4
  • Other laboratory tests should be guided by history and physical examination findings rather than performed as routine screening 1, 4
  • Consider additional testing based on specific concerns:
    • Complete blood count if infection is suspected 4
    • Electrolytes if dehydration is a concern 4
    • Radiographs if trauma or fracture is suspected 1

Special Considerations

  • Be aware that the persistence of excessive crying after the initial examination may predict a serious cause 1
  • Infants who cease crying before or during the initial assessment are less likely to have a serious cause 1
  • Consider non-obvious causes such as hair tourniquet, corneal abrasion, or even scorpion envenomation in endemic areas 1, 6
  • For infants with inconsolable crying and no obvious cause after initial evaluation, consider observation in the ED before discharge 4

Management Approach

  • If a specific cause is identified, treat accordingly 1, 4
  • If no cause is found but the child appears well, consider:
    • Discharge with close follow-up 4
    • Clear return precautions for worsening symptoms 4
    • Parent education about normal crying patterns and soothing techniques 3
  • If the child appears unwell or crying persists despite intervention, consider admission for observation and further evaluation 1, 4

Pitfalls and Caveats

  • Avoid attributing excessive crying solely to colic without a thorough evaluation, as serious conditions may be missed 1, 4
  • Remember that history and physical examination are the cornerstones of evaluation and should drive investigation selection 4
  • Be aware that some serious diagnoses may only be made on revisit, so follow-up is crucial 4
  • Consider child abuse in cases with unexplained injuries, including facial petechiae 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

An infant with inconsolable crying.

The American journal of emergency medicine, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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