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Last updated: October 25, 2025View editorial policy

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Differential Diagnosis for Nausea

  • Single most likely diagnosis:
    • Gastroenteritis: This is often the most common cause of nausea, especially if it's accompanied by vomiting, diarrhea, or abdominal cramps, due to viral or bacterial infections.
  • Other Likely diagnoses:
    • Food poisoning: Similar to gastroenteritis, food poisoning from consuming contaminated or spoiled food can lead to nausea, vomiting, and stomach cramps.
    • Motion sickness: For individuals who have recently traveled by car, boat, plane, or other vehicles, motion sickness is a common cause of nausea.
    • Pregnancy: Morning sickness is a well-known symptom of early pregnancy, characterized by nausea with or without vomiting.
    • Medication side effects: Many medications can cause nausea as a side effect, including antibiotics, pain relievers, and chemotherapy drugs.
  • Do Not Miss diagnoses:
    • Appendicitis: Although less common, appendicitis can initially present with nausea and vomiting before progressing to severe abdominal pain, and missing this diagnosis can lead to serious complications.
    • Kidney stones: Severe pain and nausea can be symptoms of kidney stones, especially if they cause an obstruction.
    • Pancreatitis: Inflammation of the pancreas can cause severe abdominal pain and nausea, and it requires immediate medical attention.
    • Heart attack: In some cases, especially in women, a heart attack can present with nausea and vomiting, among other symptoms.
  • Rare diagnoses:
    • Migraines: Some individuals experience nausea and vomiting as part of their migraine symptoms.
    • Inner ear disorders: Conditions like labyrinthitis or vestibular neuritis can cause vertigo, leading to nausea.
    • Brain tumors: Although very rare, brain tumors can cause nausea and vomiting, especially if they increase intracranial pressure.
    • Endocrine disorders: Certain endocrine conditions, such as adrenal insufficiency or thyroid disorders, can cause nausea among other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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