Can deflazacort (a corticosteroid) be used to treat tennis elbow?

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Last updated: October 25, 2025View editorial policy

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Deflazacort Is Not Recommended for Tennis Elbow Treatment

Corticosteroid injections, including deflazacort, should be used with caution in tennis elbow as they may provide short-term relief but can inhibit healing, reduce tendon strength, and potentially lead to spontaneous rupture. 1

First-Line Treatment Options for Tennis Elbow

  • Conservative management should be the initial approach for tennis elbow, focusing on relative rest while avoiding complete immobilization to prevent muscular atrophy 1, 2
  • Activities that don't worsen pain may be continued, but those that aggravate symptoms should be modified or temporarily stopped 2
  • Cryotherapy (ice application) for 10-minute periods through a wet towel provides effective short-term pain relief 1, 2
  • NSAIDs (oral or topical) effectively relieve pain, with topical NSAIDs reducing tendon pain while avoiding gastrointestinal risks 1, 2
  • Counterforce bracing/orthotics (tennis elbow bands) help reinforce, unload, and protect tendons during activity 1, 2
  • Eccentric strengthening exercises and stretching are beneficial for promoting tendon healing and increasing strength 1, 2

Second-Line Treatment Options

  • Locally injected corticosteroids may provide short-term relief but do not alter long-term outcomes 1, 2
  • Corticosteroid injections should be used with caution as they may inhibit healing and reduce tendon tensile strength 1
  • Therapeutic ultrasound may decrease pain and increase collagen synthesis, though evidence for consistent benefit is weak 1, 2
  • Extracorporeal shock wave therapy (ESWT) appears safe and effective but requires further research 1, 2

Concerns with Corticosteroid Use in Tennis Elbow

  • No evidence-based guidelines support the use of local corticosteroid injections in tendinopathy 1
  • Corticosteroids may inhibit healing and reduce the tensile strength of the tissue, predisposing to spontaneous rupture 1
  • Recent high-quality evidence suggests corticosteroids may delay recovery in tennis elbow 3
  • A randomized controlled trial showed that corticosteroid injections had significantly better effects at six weeks but with high recurrence rates (47/65 of successes subsequently regressed) and significantly poorer outcomes in the long term compared with physiotherapy 4

Treatment Algorithm

  • Initial phase (0-4 weeks): Rest, activity modification, ice application, NSAIDs, and bracing 1, 2
  • Rehabilitation phase (2-8 weeks): Progressive eccentric strengthening exercises, stretching, and continued bracing as needed 2
  • For persistent symptoms: Consider second-line modalities but use corticosteroids with caution 1, 2
  • For refractory cases (>6-12 months): Surgical consultation may be warranted 2, 5

Common Pitfalls and Caveats

  • Overreliance on corticosteroid injections may lead to tendon weakening and potential rupture 2
  • Complete immobilization should be avoided as it leads to muscle atrophy and deconditioning 1, 2
  • Tennis elbow is self-limited, with approximately 80% of cases resolving with conservative management 5
  • Advice with a "wait and see" approach is recommended as first-line treatment in primary care for most cases 6

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Treatment of Tennis Elbow (Lateral Epicondylitis)

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Editorial Commentary: Arthroscopic Debridement of Tennis Elbow Nonresponsive to Nonoperative Measures Is a Good Option and Clinical Outcomes Are Associated With Radiographic Outcomes.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2022

Research

Management of tennis elbow.

Open access journal of sports medicine, 2011

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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