Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 25, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Rib Pain with Deep Inspiration

Single Most Likely Diagnosis

  • Costochondritis: This is a common condition characterized by inflammation of the cartilage that connects the ribs to the breastbone. It is often seen in young women and can be exacerbated by deep breathing or movement. The use of birth control may also contribute to increased risk of costochondritis due to hormonal changes.

Other Likely Diagnoses

  • Musculoskeletal strain: Given the patient's age and the absence of injury, musculoskeletal strain from overuse or poor posture could be a contributing factor to her rib pain.
  • Precordial catch syndrome: This condition is characterized by sharp, stabbing pains in the chest or rib area, often precipitated by deep breathing. It is more common in young adults and can be recurrent.
  • Gastroesophageal reflux disease (GERD): Although not directly related to rib pain, GERD can cause chest pain that may radiate to the ribs, especially with deep inspiration, due to acid reflux irritating the esophagus.

Do Not Miss Diagnoses

  • Pulmonary embolism: Although less likely in a young, otherwise healthy female, pulmonary embolism is a life-threatening condition that must be considered, especially if the patient has risk factors such as recent travel, immobilization, or a family history of clotting disorders. The use of birth control can increase the risk of thromboembolic events.
  • Pneumothorax: Spontaneous pneumothorax can occur without trauma, especially in tall, thin individuals. It would cause sudden onset of sharp chest pain that worsens with deep breathing.
  • Cardiac conditions (e.g., pericarditis, myocardial infarction): While rare in young women, cardiac causes of chest pain must be considered, especially if accompanied by other symptoms like palpitations, shortness of breath, or radiation of pain to the arm, neck, or jaw.

Rare Diagnoses

  • Tietze's syndrome: Similar to costochondritis but involves inflammation of the cartilages and surrounding tissues of the ribs. It is less common and can be distinguished by the presence of swelling over the affected area.
  • Sickle cell crisis: In patients with sickle cell disease, a crisis can cause severe pain, including chest and rib pain, due to vaso-occlusion.
  • Osteoporotic rib fracture: Although rare in a young female without significant risk factors for osteoporosis, it could be considered if the patient has a history of minimal trauma or has risk factors for bone disease.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.