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Last updated: October 26, 2025View editorial policy

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Differential Diagnosis for Foot Pain

Single Most Likely Diagnosis

  • Plantar Fasciitis: This is the most common cause of foot pain, especially in the heel. It is characterized by inflammation of the plantar fascia, leading to pain and stiffness, particularly after periods of rest or at the start of the day.

Other Likely Diagnoses

  • Morton's Neuroma: A condition where a nerve in the foot becomes irritated or compressed, leading to pain, typically between the toes.
  • Achilles Tendinitis: Inflammation of the Achilles tendon, causing pain in the back of the ankle.
  • Bunions: A bony growth at the base of the big toe, leading to pain and discomfort, especially when wearing shoes.
  • Gout: A form of arthritis characterized by sudden, severe attacks of pain, swelling, redness, and tenderness, often in the big toe.

Do Not Miss Diagnoses

  • Deep Vein Thrombosis (DVT): Although less common, DVT can cause foot pain and is a potentially life-threatening condition if not treated promptly.
  • Osteomyelitis: An infection of the bone, which can cause severe pain and has significant morbidity if not diagnosed and treated appropriately.
  • Compartment Syndrome: A condition where increased pressure within a muscle compartment leads to inadequate blood supply to the tissues, causing severe pain and potentially leading to permanent damage if not promptly addressed.

Rare Diagnoses

  • Charcot Foot: A condition that affects the bones, joints, and soft tissues of the foot, often in people with diabetes, leading to severe deformity if not managed properly.
  • Erythromelalgia: A disorder characterized by burning pain, heat, and redness in the hands and feet, which can be primary or secondary to other conditions.
  • Tarsal Tunnel Syndrome: A condition that is similar to carpal tunnel syndrome but affects the nerves in the foot, causing pain, numbness, and tingling.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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