Differential Diagnosis for 80 yo Female with Hematuria and HGB 9
Single Most Likely Diagnosis
- Urinary Tract Infection (UTI) or Pneumonia leading to anemia: Given the patient's age, a UTI or pneumonia could easily lead to anemia due to chronic blood loss or inflammation, and hematuria can be a symptom of a UTI.
Other Likely Diagnoses
- Bladder Cancer: Hematuria is a common presenting symptom of bladder cancer, especially in older adults.
- Kidney Stones: While more common in younger populations, kidney stones can still occur in the elderly and cause hematuria and potentially anemia if there's significant blood loss.
- Benign Prostatic Hyperplasia (BPH) or other obstructive uropathy: In women, less common than in men, but any obstructive process can lead to urinary retention, infection, and potentially hematuria and anemia.
Do Not Miss Diagnoses
- Renal Cell Carcinoma: Although less likely than bladder cancer, renal cell carcinoma can present with hematuria and anemia, and missing this diagnosis could be fatal.
- Vasculitis (e.g., ANCA-associated vasculitis): Certain types of vasculitis can present with renal involvement, leading to hematuria and anemia, and are critical to diagnose due to their potential for severe morbidity and mortality.
- Sickle Cell Disease crisis: Though less common in an 80-year-old, if the patient has sickle cell disease, a crisis could lead to anemia and hematuria.
Rare Diagnoses
- Goodpasture Syndrome: An autoimmune disease that can cause renal failure and hematuria, though it's rare and more commonly seen in younger populations.
- Alport Syndrome: A genetic disorder affecting the type IV collagen in the kidneys, leading to hematuria, but typically presents earlier in life.
- Tubulointerstitial Nephritis: Can cause hematuria and anemia but is less common and often associated with specific drug exposures or infections.