What is the treatment for Morton's neuroma?

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Last updated: March 26, 2025View editorial policy

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From the Guidelines

Treatment for Morton's neuroma should initially focus on conservative measures, including wearing open-backed shoes, using heel lifts or orthoses, taking NSAIDs, decreasing activity, performing stretching exercises, and weight loss if indicated, as these methods have been found to be beneficial in managing symptoms 1. When managing Morton's neuroma, it's essential to prioritize approaches that reduce pressure on the affected nerve and promote comfort.

  • Key initial steps include:
    • Wearing open-backed shoes to reduce pressure on the area
    • Using heel lifts or orthoses to redistribute pressure
    • Taking NSAIDs to manage pain and inflammation
    • Decreasing activity to avoid exacerbating the condition
    • Performing stretching exercises to improve foot mechanics
    • Weight loss if indicated, to reduce overall pressure on the feet In contrast to other considerations, local injections of corticosteroids are not recommended 1, highlighting the importance of adhering to evidence-based guidelines in treatment selection. For cases that are acute or refractory, immobilization may be considered as a further conservative measure before exploring more invasive options. The goal of these treatments is to alleviate symptoms within six to eight weeks, at which point continued treatment is based on symptom resolution.

From the Research

Treatment Options for Morton's Neuroma

The treatment for Morton's neuroma can be categorized into conservative measures, minimally invasive procedures, and surgical excision.

  • Conservative measures include:
    • Orthotics 2, 3, 4
    • Anti-inflammatory medication 2
    • Shoe modifications 3
  • Minimally invasive procedures include:
    • Infiltration of the area with a corticosteroid and local anesthetic 2, 5
    • Chemical neurolysis with alcohol 2, 5
    • Radiofrequency thermal neurolysis 2
    • Capsaicin injections 5
    • Hyaluronic Acid injections 5
    • Sclerosant injections 5
  • Surgical excision is usually performed through a dorsal approach 4, 6

Efficacy of Treatment Options

  • Steroid injections have been shown to be effective in reducing pain, with 82% of patients experiencing complete or partial relief of pain at 12-month follow-up 3
  • Capsaicin injections have been reported to produce a significant reduction in pain, with a VAS score reduction of 51.8% 5
  • Corticosteroids have also been shown to be highly effective in reducing pain related to Morton's neuroma 5
  • Surgical excision is recommended as the initial treatment of choice by some authors, with a high success rate 6

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Ultrasound-guided treatment of Morton's neuroma.

Journal of ultrasonography, 2021

Research

Morton's neuroma - Current concepts review.

Journal of clinical orthopaedics and trauma, 2020

Research

Infiltrative Treatment of Morton's Neuroma: A Systematic Review.

Pain management nursing : official journal of the American Society of Pain Management Nurses, 2024

Research

A comparative analysis of conservative versus surgical treatment of Morton's neuroma.

Journal of the American Podiatric Medical Association, 1989

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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