What are the recommendations for post-operative care?

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Last updated: October 26, 2025View editorial policy

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Recommendations for Post-Operative Care

Multimodal analgesia that includes regular nonsteroidal anti-inflammatory drugs and paracetamol is strongly recommended as the foundation of post-operative pain management. 1

Pain Management

  • Implement a multimodal approach to pain control using scheduled acetaminophen and NSAIDs as first-line agents, with opioids reserved only for breakthrough pain 1, 2
  • Consider wound catheters or local abdominal wall blocks to reduce postoperative opioid requirements, although efficacy may vary 1, 3
  • Thoracic epidural analgesia should be used only after assessment for sepsis and abnormal coagulation, with appropriate monitoring for hypotension 1
  • Avoid routine use of long-acting sedatives preoperatively as they provide no clinical benefit 1

Early Mobilization

  • Early mobilization after surgery is strongly recommended to prevent complications such as venous thromboembolism, pulmonary issues, and muscle weakness 1
  • Aim for at least 30 minutes of mobilization on the day of surgery and 6 hours per day thereafter 3
  • For older patients with frailty, implement patient-oriented rehabilitation to reduce mortality and improve functional outcomes 1

Nutrition and Fluid Management

  • Resume a regular diet within 2 hours after surgery when appropriate (particularly after cesarean delivery) 1
  • Avoid fluid overloading as it can worsen intestinal edema and prolong ileus 1, 4
  • Aim for near-zero fluid balance to improve outcomes 1

Venous Thromboembolism (VTE) Prevention

  • Assess patients with a validated tool for VTE risk on admission and throughout hospital stay 1
  • Use mechanical prophylaxis (pneumatic compression stockings) for all patients undergoing surgery 1
  • For high-risk patients, combine pharmacological with mechanical prophylaxis 1
  • Continue VTE risk assessment and appropriate prophylaxis daily during the postoperative period 1

Preventing and Managing Postoperative Ileus

  • Remove nasogastric tubes as early as possible as routine use does not improve outcomes 1, 4
  • Consider using prokinetic agents, bisacodyl, and magnesium oxide to promote bowel function 5, 4
  • Chewing gum after surgery may help stimulate bowel function through cephalic-vagal stimulation 4

Preventing and Managing Delirium

  • Patients over 65 years of age should receive regular postoperative delirium screening 1
  • Implement non-pharmaceutical interventions such as regular orientation, sleep hygiene approaches, and cognitive stimulation to prevent delirium 1
  • Minimize medication triggers that can precipitate delirium 1

Wound Care and Infection Prevention

  • Antimicrobial prophylaxis should be used in a single-dose manner initiated 30-60 minutes before skin incision 1
  • For contaminated or potentially contaminated surgery, consider extending prophylactic antibiotics for 24 hours postoperatively 6
  • In surgery where infection would be particularly devastating (e.g., open-heart surgery, prosthetic arthroplasty), prophylactic antibiotics may be continued for 3-5 days 6

Postoperative Monitoring and Level of Care

  • Establish protocols for determining appropriate location for postoperative care based on validated preoperative risk scores, surgical impact, physiological stability, and ongoing therapeutic requirements 1
  • Consider ICU admission for high-risk emergency laparotomy patients to reduce mortality and length of stay 1
  • Monitor for persistent hypothermia and use forced-air warming blankets, raised ambient room temperature, and warming of irrigation and IV fluids to prevent it 1

Special Considerations

  • For cesarean delivery, early feeding within 2 hours is strongly recommended 1
  • Maintain tight control of capillary blood glucose in the postoperative period 1
  • Remove urinary catheters immediately after cesarean delivery if placed during surgery 1

Discharge Planning

  • Provide standardized written discharge instructions to facilitate discharge counseling 1
  • For patients undergoing laparoscopic myomectomy, advise avoiding heavy lifting, strenuous exercise, and sexual activity for at least 2-3 weeks 3
  • Schedule follow-up appointments 2-4 weeks after surgery to assess healing and recovery 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

New Advances in Acute Postoperative Pain Management.

Current pain and headache reports, 2018

Guideline

Post-Operative Care for Laparoscopic Myomectomy

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Ileus

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Intractable Hiccups from Ileus

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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