What questions should be asked to diagnose a patient's condition?

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Last updated: October 27, 2025View editorial policy

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Diagnostic Questions for Common Medical Conditions

Ménière's Disease

To diagnose Ménière's disease, physicians should ask specific questions about vertigo episodes, hearing symptoms, and their temporal relationship.

  • Ask about the nature of dizziness, specifically whether the patient experiences a sensation of spinning or rotation (true vertigo) 1
  • Inquire about the duration of vertigo episodes (typically lasting 20 minutes to 24 hours in Ménière's disease) 1
  • Ask about the frequency of vertigo attacks 1
  • Determine if hearing loss occurs with dizziness episodes, and whether it fluctuates 1
  • Ask about tinnitus (ringing, buzzing, or other noises in the ear) during or between attacks 1
  • Inquire about aural fullness (ear feeling plugged) during episodes 1
  • Ask if symptoms have caused falls 1
  • Determine if headaches or light sensitivity occur during dizzy spells (to rule out vestibular migraine) 1
  • Ask about family history of similar symptoms 1

Allergic Rhinitis

When evaluating a patient for allergic rhinitis, focus questions on symptom patterns, triggers, and impact on quality of life.

  • Determine the pattern of nasal symptoms (seasonal, perennial, or combined) 1
  • Ask about specific nasal symptoms: congestion, rhinorrhea, sneezing 1
  • Inquire about the onset, frequency, and characteristics of symptoms 1
  • Identify potential triggers that precipitate or worsen symptoms (pollen, animals, irritants) 1
  • Ask about associated symptoms: throat soreness, post-nasal drip, cough, ocular symptoms 1
  • Determine the severity and impact on quality of life, including work/school performance and sleep 1
  • Ask about previous treatments and their effectiveness 1
  • Inquire about willingness to modify exposures if allergens are identified 1

Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis

For suspected SJS/TEN, ask detailed questions about medication history, symptom progression, and mucosal involvement.

  • Ask about prodromal symptoms (fever, malaise, upper respiratory symptoms) 1
  • Determine the date when the rash first appeared and document progression 1
  • Ask about pain associated with the rash 1
  • Inquire about involvement of mucosal sites (eyes, mouth, nose, genitalia) 1
  • Ask about respiratory symptoms: cough, dyspnoea, bronchial hypersecretion, haemoptysis 1
  • Inquire about gastrointestinal symptoms: diarrhoea, abdominal distension 1
  • Record all medications taken over the previous 2 months, including over-the-counter and complementary therapies 1
  • Document when medications were started, dose changes, and when they were stopped 1
  • Ask about previous history of drug allergies and reaction types 1

Alzheimer's Disease and Related Disorders

When evaluating for cognitive impairment, ask questions about changes in memory, function, and behavior.

  • Inquire about changes in cognitive abilities over the previous year 1
  • Ask about difficulties with complex instrumental activities of daily living (managing finances, using technology, traveling to unfamiliar areas) 1
  • Determine if there are problems with basic self-care activities (bathing, dressing, toileting) 1
  • Ask about changes in behavior or personality 1
  • Inquire about neuropsychiatric symptoms: apathy, depression, anxiety, irritability, agitation 1
  • Ask about sleep disturbances 1
  • Determine if there is a family history of dementia 2
  • Use open-ended questions to explore the patient's understanding of their symptoms 3
  • Consider using validated assessment tools like the AD8, ECog, or CFI 1

Overactive Bladder

For diagnosing overactive bladder, focus questions on urinary urgency, frequency, and associated symptoms.

  • Ask if the patient experiences a sudden, compelling desire to pass urine that is difficult to defer (urgency) 1
  • Determine the number of urination episodes during waking hours (frequency) 1
  • Ask about nocturia (waking at night to urinate) and the number of episodes 1
  • Inquire about urgency urinary incontinence (leakage associated with urgency) 1
  • Ask about the duration of symptoms 1
  • Determine if symptoms are bothersome to the patient 1
  • Review current medications that might affect bladder function 1
  • Ask about co-morbid conditions, especially neurologic diseases 1
  • Inquire about the impact of symptoms on quality of life 1

General Approach to Diagnostic Questioning

Use open-ended questions initially, followed by focused inquiries to gather comprehensive information efficiently.

  • Begin with open-ended questions like "What brings you in today?" or "What can I do for you?" to allow patients to describe their concerns freely 4, 5
  • Ask about the onset and chronology of symptoms 2
  • Inquire about the location of symptoms and if they radiate 2
  • Ask patients to describe how symptoms feel (quality) 2
  • Determine the severity of symptoms and their impact on daily activities 2
  • Ask about the duration of symptoms 2
  • Identify activities or situations when symptoms occur or worsen 2
  • Ask what makes symptoms better or worse 2
  • Inquire about associated symptoms 2
  • Use the question "What is your understanding of your illness?" to explore patients' perspectives 3
  • Ask patients what specific needs they hope to address during the visit 6
  • Allow sufficient time for patients to express their concerns before moving to focused questions 1

Documentation and Follow-up

Document pertinent positive and negative findings to support diagnostic reasoning.

  • Record both the presence and absence of key symptoms relevant to the suspected diagnosis 2
  • Document the patient's description of symptoms in their own words when possible 7
  • Note the impact of symptoms on the patient's quality of life and daily functioning 7
  • Consider using standardized assessment tools or symptom questionnaires when appropriate 1
  • Ask patients about their expectations regarding diagnosis and treatment 7, 6
  • Provide patients with written information about their condition after diagnosis 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Essential Components of the History of Present Illness (HPI)

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Effective Communication During Primary Care Appointments

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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