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Last updated: October 27, 2025View editorial policy

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Differential Diagnosis for Mucus in Urine

  • Single most likely diagnosis
    • Urinary Tract Infection (UTI): This is the most common cause of mucus in urine, as the body's response to infection often includes the production of mucus to trap pathogens.
  • Other Likely diagnoses
    • Kidney Stones: The presence of stones can irritate the urinary tract, leading to inflammation and increased mucus production.
    • Benign Prostatic Hyperplasia (BPH): Enlargement of the prostate can cause urinary retention, leading to stasis of urine and subsequent infection or irritation that results in mucus production.
    • Interstitial Cystitis: A condition characterized by bladder inflammation, which can cause a range of symptoms including the presence of mucus in the urine.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Bladder Cancer: Although less common, bladder cancer can cause changes in urine, including the presence of mucus, and is critical to diagnose early for effective treatment.
    • Tuberculosis of the Urinary Tract: A serious infection that can cause significant morbidity if not treated promptly, and may present with mucus in the urine among other symptoms.
  • Rare diagnoses
    • Schistosomiasis: A parasitic infection that can affect the urinary tract, leading to symptoms including hematuria and the presence of mucus in urine, more common in specific geographic regions.
    • Malacoplakia: A rare condition characterized by the formation of plaques in the urinary tract, which can cause a range of urinary symptoms including the presence of mucus.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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