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Last updated: October 27, 2025View editorial policy

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Differential Diagnosis for Pruritic Patches All Over the Body

Single Most Likely Diagnosis

  • Atopic Dermatitis (Eczema): This is the most common cause of pruritic patches and is characterized by dry, itchy, and inflamed skin. It often starts in childhood but can persist into adulthood.

Other Likely Diagnoses

  • Contact Dermatitis: An allergic or irritant reaction to substances like soaps, detergents, or metals, leading to itchy patches.
  • Psoriasis: An autoimmune condition causing red, scaly, and itchy patches, often on the elbows, knees, and scalp.
  • Seborrheic Dermatitis: A condition causing scaly patches, red skin, and stubborn dandruff, often due to a yeast infection.
  • Urticaria (Hives): Itchy, raised welts that can appear anywhere on the body, often due to an allergic reaction.

Do Not Miss Diagnoses

  • Bullous Pemphigoid: An autoimmune disease causing large, itchy blisters, which can be life-threatening if not treated.
  • Cutaneous T-Cell Lymphoma (Mycosis Fungoides): A rare type of skin cancer that can cause itchy patches, which is critical to diagnose early.
  • Scabies: A parasitic infection causing intense itching, especially at night, which can lead to secondary infections if not treated.

Rare Diagnoses

  • Pityriasis Rubra Pilaris: A rare skin disorder causing constant itching, scaling, and redness.
  • Dermatitis Herpetiformis: A skin manifestation of celiac disease, characterized by itchy blisters.
  • Erythroderma (Exfoliative Dermatitis): A condition causing widespread redness, scaling, and itching, often due to underlying skin conditions or medications.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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