What are the complications of cardiac catheterization (cardiac cath)?

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Last updated: March 26, 2025View editorial policy

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From the Guidelines

Cardiac catheterization complications can be categorized into major and minor adverse events, including cardiac structure perforation, injury, or compromise, new pericardial effusion, coronary obstruction, and coronary artery access difficulties, as defined by the Valve Academic Research Consortium 3 1.

Complications of Cardiac Catheterization

The complications of cardiac catheterization can occur during or after the procedure and may include:

  • Cardiac structural complications, such as injury to the aortic annulus, left ventricle outflow tract, ventricular septum, left or right ventricle, atrial septum, left or right atrium, mitral valve apparatus, tricuspid valve apparatus, coronary artery, and coronary sinus 1
  • Vascular complications, such as bleeding or hematoma at the access site, pseudoaneurysm, arteriovenous fistula, or retroperitoneal bleeding 1
  • Contrast-induced nephropathy, which affects 2-25% of patients, particularly those with pre-existing kidney disease or diabetes 1
  • Allergic reactions to contrast media, which happen in about 1% of procedures 1
  • More serious but less frequent complications, such as stroke (0.1-0.4%), myocardial infarction (0.05-0.1%), arrhythmias, coronary artery dissection or perforation, and death (0.1-0.2%) 1

Risk Factors and Prevention Strategies

Risk factors for complications include advanced age, female gender, renal insufficiency, and complex procedures 1. Prevention strategies include:

  • Proper patient selection
  • Adequate hydration before and after the procedure
  • Minimizing contrast volume
  • Using radial rather than femoral access when possible
  • Careful technique
  • Post-procedure monitoring for several hours to detect and manage complications early 1 The overall risk-benefit ratio strongly favors performing cardiac catheterization when clinically indicated, with most complications being successfully managed if identified promptly 1.

From the Research

Complications of Cardiac Catheterization

The complications of cardiac catheterization (cardiac cath) can be categorized into several types, including:

  • Vascular access complications, such as hematoma, pseudoaneurysm, arteriovenous fistula, peripheral artery occlusion and dissection, and retroperitoneal bleeding 2
  • Bleeding complications, such as major and minor bleeding, and retroperitoneal hemorrhage 3
  • Access site complications, such as hematoma, pseudoanurysm, and arteriovenous fistula 4

Risk Factors for Complications

Several risk factors have been identified for complications after cardiac catheterization, including:

  • Use of anticoagulation therapy, such as warfarin or direct acting oral anticoagulant 5
  • History of vascular complication after prior interventional cardiology procedure 3
  • Female sex and age ≥60 years 3
  • Use of large introducer sheaths (>6F) and percutaneous coronary intervention 3

Strategies for Decreasing Complications

Several strategies have been proposed to decrease vascular complications in diagnostic cardiac catheterization patients, including:

  • Use of radial artery access instead of femoral artery access 6, 2
  • Less aggressive anticoagulation regimen during transfemoral interventions 6
  • Use of closure devices to reduce bleeding complications 6
  • Frequent assessment of the access site and patient education to identify complications early 4

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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