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Differential Diagnosis for Cheeks Rash

Single Most Likely Diagnosis

  • Erythema Infectiosum (Fifth Disease): A common childhood illness caused by parvovirus B19, characterized by a distinctive "slapped-cheek" appearance, making it a leading consideration for a cheeks rash.

Other Likely Diagnoses

  • Rosacea: An inflammatory skin condition that can cause redness, acne-like symptoms, and flushing on the cheeks, among other areas of the face.
  • Contact Dermatitis: An allergic or irritant reaction to substances like cosmetics, soaps, or metals, which can lead to a rash on the cheeks.
  • Acne: Although more commonly associated with the forehead and chin, acne can also occur on the cheeks, especially in individuals with oily skin or during puberty.
  • Eczema (Atopic Dermatitis): A chronic condition that can cause dry, itchy, and inflamed skin, including on the cheeks, particularly in children and individuals with allergies.

Do Not Miss Diagnoses

  • Lupus Erythematosus: A systemic autoimmune disease that can cause a characteristic butterfly-shaped rash across the cheeks and nose, which is crucial to identify due to its potential for serious complications.
  • Sarcoidosis: An autoimmune disease that can lead to skin lesions, including on the cheeks, and requires early diagnosis to manage its systemic effects.
  • Cellulitis: A bacterial skin infection that can cause redness, swelling, and warmth, potentially on the cheeks, which needs prompt antibiotic treatment to prevent serious outcomes.

Rare Diagnoses

  • Sjögren's Syndrome: An autoimmune disorder that can cause skin rashes, among other symptoms like dry eyes and mouth, though it's less commonly associated with isolated cheek rashes.
  • Dermatomyositis: An inflammatory disease characterized by skin rash and muscle weakness, with the rash sometimes appearing on the cheeks, though it's a rare condition.
  • Granuloma Faciale: A rare skin condition causing reddish-brown plaques or patches, typically on the face, including the cheeks, which can be challenging to treat.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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