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Last updated: October 27, 2025View editorial policy

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Differential Diagnosis for Pump with Pus on Scalp

  • Single most likely diagnosis
    • Furuncle or Carbuncle: This is the most likely diagnosis given the description of a "pump with pus" on the scalp. A furuncle (boil) is an infection of the hair follicle, and when several furuncles merge, they form a carbuncle. Both conditions are typically caused by Staphylococcus aureus and present with a painful, pus-filled nodule or mass.
  • Other Likely diagnoses
    • Abscess: An abscess is a collection of pus that has built up within the tissue of the body, which could occur on the scalp. It's similar to a furuncle or carbuncle but might not be centered on a hair follicle.
    • Folliculitis: This is an inflammatory condition affecting the hair follicles, often caused by bacterial infection. It can present with pus-filled bumps on the scalp.
    • Infected epidermoid cyst: These are benign cysts that can become infected, leading to a painful, pus-filled lesion that could resemble a "pump with pus."
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Meningitis or brain abscess (especially if there's a history of trauma or the patient shows signs of neurological deficit): Although less common, an infection on the scalp could potentially spread to the brain, especially if it's related to a traumatic injury or if the patient has a compromised immune system.
    • Osteomyelitis of the skull: This is an infection of the bone, which could occur if the infection spreads from the scalp to the underlying bone.
  • Rare diagnoses
    • Kerion: A severe form of tinea capitis (ringworm of the scalp) that can cause a painful, pus-filled mass. It's more common in children.
    • Mycetoma: A chronic, granulomatous infection of the skin and subcutaneous tissue caused by fungi or bacteria, which can present with pus-filled lesions. It's rare in most parts of the world but should be considered in endemic areas or in patients who have traveled to such areas.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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