Recommended Weekly Alcohol Limits in Units
The recommended weekly alcohol limit is no more than 14 units for women and 21 units for men, with at least one alcohol-free day per week to reduce health risks including liver disease, cardiovascular complications, and cancer. 1
Understanding Alcohol Units
- A standard drink or unit varies by country: 8g of pure alcohol in the UK, 10g in Europe, 14g in the US, and 23.5g in Japan 1
- Common examples of one standard drink (UK definition):
- 12 oz (356 ml) of beer
- 5 oz (148 ml) of wine
- 1.5 oz (44.4 ml) of distilled spirits 1
Evidence-Based Recommendations
General Population Guidelines
- Weekly consumption should not exceed 10 standard drinks to avoid overall health risks 1
- Daily consumption should be limited to 1-2 standard drinks per day 1
- At least 2 alcohol-free days per week are recommended 1
Sex-Specific Guidelines
- Men: No more than 21 units (standard drinks) per week 1
- Women: No more than 14 units (standard drinks) per week 1
- Older adults (≥65 years): Should follow the lower limits recommended for women (≤7 drinks per week) 1
Health Risks Associated with Alcohol Consumption
Liver Disease Risk
- Risk of cirrhosis increases significantly with alcohol consumption:
- The threshold for hepatotoxic alcohol consumption varies by region:
Cardiovascular Risk
- Blood pressure increases in a dose-dependent manner with alcohol consumption 2
- Risk of atrial fibrillation increases 10% for every standard drink above 14g/day 2
- The European Society of Cardiology recommends:
- Less than 14 units/week for men
- Less than 8 units/week for women 1
Cancer Risk
- Alcohol consumption is associated with multiple cancers including breast, colon, liver, esophageal, oral cavity, and pharyngeal cancers 1
- Risk of hepatocellular carcinoma (HCC) increases with daily consumption above 50-60g 1
- More than 50% of alcohol-caused cancer deaths occur in people drinking within weekly limits 3
Pattern of Drinking Matters
- Binge drinking (≥5 drinks for men, ≥4 drinks for women in one sitting) increases risk of alcohol-related liver disease and all-cause mortality 1
- Drinking outside of meal times increases risk of alcohol-related liver disease by 2.7-fold 1
- Daily drinking carries a higher risk than less frequent drinking, with relative risk of 3.65 for daily consumption versus 1.34 for those who drink less than once a week 1
Special Populations
- Women are twice as sensitive to alcohol-mediated hepatotoxicity and may develop more severe alcohol-related liver disease at lower doses 1
- Pregnant women should abstain from alcohol completely 1
- People with existing liver conditions or taking medications that interact with alcohol should consider abstinence 1
Risk Assessment
- Exceeding daily drinking limits is strongly associated with alcohol use disorders, with risk increasing in a fairly linear fashion with frequency 4
- Even those drinking within guidelines are not completely protected from harm - they experience more deaths and hospitalizations than abstainers 3
- Recent evidence suggests that guidelines of around one drink per day may be most appropriate for high-income countries 3