Systemic Lupus Erythematosus (SLE): This condition is a strong candidate due to the presence of ANA+, which is a hallmark of SLE. Hyperferritinemia can occur in SLE due to chronic inflammation, and anemia along with thrombocytopenia are common hematological manifestations.

Rheumatoid Arthritis (RA): Although less directly linked to ANA+ than SLE, RA can present with anemia of chronic disease, hyperferritinemia due to inflammation, and occasionally thrombocytopenia. The presence of ANA can also be seen in RA, though it's less specific.
Chronic Inflammatory Conditions: Conditions like chronic infections or inflammatory bowel disease can lead to anemia of chronic disease, which may present with hyperferritinemia. Thrombocytopenia can occur due to splenic sequestration or as part of the inflammatory process.
Hemophagocytic Lymphohistiocytosis (HLH): Although more commonly associated with severe symptoms, HLH can present with hyperferritinemia, anemia, and thrombocytopenia. The presence of ANA might be seen in the context of an underlying autoimmune trigger.

Malignancy (e.g., Lymphoma): Certain malignancies, particularly lymphomas, can present with hyperferritinemia, anemia, and thrombocytopenia. ANA positivity can sometimes be seen in paraneoplastic syndromes.
Severe Infections (e.g., Sepsis): Sepsis can lead to a systemic inflammatory response syndrome (SIRS) with hyperferritinemia, anemia, and thrombocytopenia. Although ANA+ is not a typical marker, it could be seen in the context of a post-infectious autoimmune phenomenon.
Applastic Anemia: Although typically presenting with pancytopenia, some forms of aplastic anemia can have a more limited cytopenia presentation. Hyperferritinemia can occur due to iron overload from transfusions, and ANA might be positive in some cases.

Gaucher's Disease: A lysosomal storage disorder that can lead to anemia, thrombocytopenia, and hyperferritinemia due to chronic inflammation and iron overload. ANA positivity might be seen due to the chronic inflammatory state.
Porphyria Cutanea Tarda: A disorder of porphyrin metabolism that can lead to iron overload (hyperferritinemia) and occasionally anemia and thrombocytopenia. ANA might be positive in some cases due to associated autoimmune phenomena.
Autoimmune Hemolytic Anemia (AIHA) with Iron Overload: Although primarily causing anemia, AIHA can lead to hyperferritinemia due to hemolysis and subsequent iron overload. Thrombocytopenia can occur due to splenic sequestration, and ANA might be positive in the context of an underlying autoimmune disorder.