Diagnosis of Deep Tissue Injury
The most accurate diagnosis of deep tissue injury (DTI) requires a combination of thorough history assessment, visual skin examination with attention to skin tone differences, and appropriate imaging studies when indicated.
Clinical Presentation and Assessment
- DTI presents with purple or maroon discoloration in light skin tones, with defined borders and often surrounding erythema 1
- In patients with dark skin tones, persistent erythema and hyperpigmentation, rather than blanching, should be used to identify pressure injury 1
- Thorough history is essential to account for periods of pressure exposure, such as "time down" at the scene or periods when the patient was immobile 1
- DTI often begins in muscle tissue closest to the bone and may not be visible in early stages, with rapid deterioration despite preventive interventions 2
- Most common locations include the skin over the coccyx, sacrum, buttocks, and heels 2
Differential Diagnosis
- DTI must be differentiated from stage 2 pressure ulcers, incontinence-associated dermatitis, skin tears, bruising, hematoma, venous engorgement, arterial insufficiency, necrotizing fasciitis, and terminal skin ulcers 1
- Atypical presentations can lead to delays in necessary aggressive care or overzealous treatment for self-limiting conditions 3
- The National Pressure Ulcer Advisory Panel (NPUAP) guidelines provide descriptions of typical presentations, but many patients present atypically 3
Diagnostic Techniques
Thermographic Assessment
- Early DTI may show an increase of about 0.5°C in skin surface temperatures during initial inflammation, followed by a surface temperature decrease of about 0.2°C during persistent deep tissue ischemia 4
- These temperature differences can be detected by thermographic imaging, potentially allowing earlier diagnosis 4
Anatomical Assessment
- The Compression Intensity Index (CII) can help estimate loading intensity in muscle tissue during sitting in wheelchair users 5
- CII depends on body weight, radius of curvature of the ischial tuberosities, and thickness of underlying gluteus muscles 5
- This index can serve as a practical approximation of loading intensity in muscles of wheelchair-bound or bedridden patients 5
Risk Factors
- Advanced age and lower body mass index are associated with higher risk of DTI compared to other pressure injuries 2
- Patients with impaired motosensory capacities are at particularly high risk 5
- Sustained tissue loading and ischemic injury contribute to DTI development 4
Clinical Pitfalls and Considerations
- Early detection is challenging as lesions may not become visible on the skin surface until reaching an advanced stage 4
- DTI can rapidly deteriorate despite appropriate preventive interventions 2
- By 2010, DTIs accounted for about 9% of all pressure injuries and were more prevalent than stage 3 or 4 pressure injuries 2
- Working knowledge of dermatology is needed to distinguish DTI from other conditions that can present with similar purple hue or rapidly developing eschar 1