What is the ICD-10 code for Nicotine Stomatitis (nicotine-induced mouth sore) or Vaper's Mouth (vaping-related mouth sore)?

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ICD-10 Code for Nicotine Stomatitis or Vaper's Mouth

The appropriate ICD-10 code for nicotine stomatitis or vaper's mouth is K13.24 (Nicotine stomatitis).

Understanding Nicotine Stomatitis

Nicotine stomatitis is characterized by:

  • Inflammation of minor salivary glands in the hard palate due to chronic smoking or nicotine exposure 1
  • Typically presents with multiple red discrete papules in the hard palate surrounded by grayish-white areas 1
  • May present as red and painful sores in the mouth, as in the case described 1
  • Usually resolves within 2-4 weeks after cessation of the smoking habit 1

Clinical Presentation and Diagnosis

  • Patients with nicotine stomatitis are often asymptomatic, but may present with painful oral lesions 1
  • The condition is directly associated with tobacco use, including cigarettes, pipes, and newer products like e-cigarettes (vaping) 2
  • Vaping refers to the inhaling and exhaling of aerosols produced by e-cigarettes, which usually contain nicotine, the addictive ingredient in tobacco 2
  • Chronic overuse of nicotine replacement products can also lead to development of oral hyperkeratotic lesions 3

Differential Diagnosis

When evaluating oral lesions related to nicotine use, consider:

  • Aphthous stomatitis (ICD-10: K12.0) - interestingly, tobacco use may actually protect against this condition 4, 5
  • Oral nicotine-associated keratosis - hyperkeratotic lesions directly associated with chronic overuse of nicotine replacement products 3
  • Other tobacco-related oral mucosal lesions with potential malignant transformation 3

Management Considerations

  • Primary treatment involves cessation of the nicotine exposure (smoking, vaping, or excessive NRT use) 1
  • For symptomatic relief:
    • Bland, non-alcoholic, sodium bicarbonate-containing mouthwash used 4-6 times daily (can be increased to hourly if needed) 2
    • Adequate pain management with anesthetic mouthwashes (viscous lidocaine 2%), coating agents, or systemic analgesics following the WHO pain management ladder 2
    • For moderate pain, topical NSAIDs (e.g., amlexanox 5% oral paste) may be considered 2

Important Clinical Considerations

  • Nicotine is well absorbed from multiple routes, including mucosal surfaces, which can lead to various side effects 6
  • Irritation, burning, and pain in the mouth and throat are common side effects of oral nicotine exposure and are mediated by transient receptor potential (TRP) channels 7
  • Symptoms of nicotine toxicity typically resolve within 12 hours if the exposure is discontinued 6
  • Dental practitioners should be aware of oral effects associated with nicotine products when offering smoking cessation advice 3

Documentation Tips

  • When coding nicotine stomatitis, use K13.24 (Nicotine stomatitis)
  • Document the specific nicotine source (cigarettes, vaping, nicotine replacement therapy)
  • Note duration and characteristics of the lesions
  • Record any cessation advice provided to the patient

References

Research

Nicotina Stomatitis - A Report of Two Cases.

Journal of pharmacy & bioallied sciences, 2023

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Smokeless tobacco use prevents aphthous stomatitis.

Oral surgery, oral medicine, and oral pathology, 1992

Research

Nicotine replacement therapy as a treatment for complex aphthosis.

The Journal of dermatological treatment, 2010

Guideline

Nicotine Patch Adverse Effects

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

The Role of TRP Channels in Nicotinic Provoked Pain and Irritation from the Oral Cavity and Throat: Translating Animal Data to Humans.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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