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Last updated: October 28, 2025View editorial policy

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Differential Diagnosis for a Child with a Temperature of 101F

  • Single Most Likely Diagnosis
    • Viral upper respiratory tract infection (e.g., common cold, flu): This is the most common cause of fever in children and is often accompanied by other symptoms such as cough, runny nose, and sore throat.
  • Other Likely Diagnoses
    • Bacterial pharyngitis (e.g., strep throat): This condition can cause fever, sore throat, and swollen lymph nodes, and is more common in school-aged children.
    • Otitis media (ear infection): This is a common cause of fever in young children, especially those under the age of 2, and is often accompanied by ear pain and pulling at the ears.
    • Gastroenteritis (stomach flu): This can cause fever, vomiting, and diarrhea, and is often spread through contaminated food or water.
  • Do Not Miss Diagnoses
    • Meningitis: Although less common, meningitis is a life-threatening condition that requires prompt diagnosis and treatment. Symptoms can include fever, headache, stiff neck, and vomiting.
    • Sepsis: This is a potentially life-threatening condition that occurs when the body's response to an infection becomes uncontrolled and causes widespread inflammation. Symptoms can include fever, tachycardia, and hypotension.
    • Appendicitis: This is a surgical emergency that can cause fever, abdominal pain, and vomiting, and requires prompt diagnosis and treatment.
  • Rare Diagnoses
    • Kawasaki disease: This is a rare condition that causes fever, rash, and swollen lymph nodes, and can lead to serious cardiac complications if left untreated.
    • Juvenile idiopathic arthritis: This is a chronic condition that can cause fever, joint pain, and swelling, and can be difficult to diagnose.
    • Leukemia or lymphoma: These are rare but serious conditions that can cause fever, fatigue, and weight loss, and require prompt diagnosis and treatment.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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