What is the revised psychiatric diagnosis for a patient taking Lexapro (Escitalopram Oxalate), Remeron (Mirtazapine), Seroquel (Quetiapine Fumarate), and Cymbalta (Duloxetine HCl), with a history of encephalopathy, seizures, dysphagia, and speech and language deficits following a cerebrovascular disease, and allergies to Gabapentin, sulfa antibiotics, and sulfadiazine?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 27, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis

The patient's presentation and medication regimen suggest a complex psychiatric and medical history. The following differential diagnosis is organized into categories:

  • Single Most Likely Diagnosis
    • Dementia with Behavioral Disturbances: The patient's history of encephalopathy, seizures, and cerebrovascular disease, combined with her argumentative and combative behavior, suggests a diagnosis of dementia with behavioral disturbances. The use of medications such as Seroquel (Quetiapine Fumarate) and Remeron (Mirtazapine) also supports this diagnosis, as they are commonly used to manage behavioral symptoms in dementia patients.
  • Other Likely Diagnoses
    • Major Depressive Disorder: The patient's medication regimen includes Lexapro (Escitalopram Oxalate), Cymbalta (Duloxetine HCl), and Remeron (Mirtazapine), which are commonly used to treat depression. Although the patient reports stable mood, her medication history suggests a possible diagnosis of major depressive disorder.
    • Anxiety Disorder: The patient's use of Lexapro (Escitalopram Oxalate) and Cymbalta (Duloxetine HCl) also suggests a possible diagnosis of an anxiety disorder, such as generalized anxiety disorder or social anxiety disorder.
    • Bipolar Disorder: The patient's medication regimen includes Seroquel (Quetiapine Fumarate), which is sometimes used to treat bipolar disorder. Although there is no clear indication of manic or hypomanic episodes, the use of this medication suggests a possible diagnosis of bipolar disorder.
  • Do Not Miss Diagnoses
    • Delirium: The patient's history of encephalopathy and seizures increases her risk for delirium. Although the patient appears pleasant and cooperative during the assessment, her argumentative and combative behavior at other times suggests a possible diagnosis of delirium.
    • Traumatic Brain Injury: The patient's history of encephalopathy and seizures may be related to a traumatic brain injury. This diagnosis should not be missed, as it can have significant implications for the patient's treatment and management.
  • Rare Diagnoses
    • Frontotemporal Dementia: The patient's behavioral disturbances and history of cerebrovascular disease may suggest a diagnosis of frontotemporal dementia. Although this diagnosis is less likely, it should be considered in the differential diagnosis due to the patient's unique presentation.
    • Creutzfeldt-Jakob Disease: The patient's history of encephalopathy and seizures may suggest a diagnosis of Creutzfeldt-Jakob disease, a rare and degenerative brain disorder. Although this diagnosis is unlikely, it should be considered in the differential diagnosis due to the patient's complex medical history.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.