Differential Diagnosis for Intrauterine Bleed
Single Most Likely Diagnosis
- Placenta Previa: This condition, where the placenta partially or completely covers the internal cervical os, is a common cause of intrauterine bleeding, especially in the second and third trimesters. It is often associated with painless vaginal bleeding.
Other Likely Diagnoses
- Placental Abruption: Also known as placental abruption, this condition involves the premature separation of the placenta from the uterus. It can cause intrauterine bleeding and is often associated with painful vaginal bleeding.
- Uterine Rupture: Although less common, uterine rupture can cause significant intrauterine bleeding, especially in women with a history of uterine surgery or previous uterine rupture.
- Molar Pregnancy: A molar pregnancy, also known as hydatidiform mole, can cause intrauterine bleeding due to the abnormal growth of trophoblast cells.
Do Not Miss Diagnoses
- Uterine Artery Aneurysm or Pseudoaneurysm: These vascular abnormalities can cause significant intrauterine bleeding and are often associated with a history of uterine surgery, trauma, or previous uterine artery embolization.
- Uterine Cancer: Although rare, uterine cancer can cause intrauterine bleeding, especially in postmenopausal women.
- Intrauterine Fetal Demise: Intrauterine fetal demise can cause intrauterine bleeding, especially if the fetus has been dead for an extended period.
Rare Diagnoses
- Vasa Previa: This rare condition involves the fetal blood vessels crossing over or near the internal cervical os, which can cause significant intrauterine bleeding if ruptured.
- Choriocarcinoma: A rare type of gestational trophoblastic disease, choriocarcinoma can cause intrauterine bleeding due to the abnormal growth of trophoblast cells.
- Uterine Arteriovenous Malformation: This rare vascular anomaly can cause significant intrauterine bleeding due to the abnormal connection between uterine arteries and veins.