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Last updated: October 29, 2025View editorial policy

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Differential Diagnosis for Vomiting

  • Single most likely diagnosis:
    • Gastroenteritis: This is often the most common cause of vomiting, especially in children and young adults, due to its high prevalence and the ease with which gastrointestinal viruses are transmitted.
  • Other Likely diagnoses:
    • Food poisoning: Similar to gastroenteritis, food poisoning is a common cause of vomiting, resulting from the consumption of contaminated or spoiled food.
    • Viral gastroenteritis (stomach flu): This condition is highly contagious and can cause severe vomiting, among other symptoms like diarrhea and abdominal cramps.
    • Motion sickness: For individuals prone to it, motion sickness can induce vomiting during travel by car, boat, plane, or other vehicles.
    • Pregnancy-related morning sickness: Although it's called "morning sickness," the nausea and vomiting associated with pregnancy can occur at any time of day.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.):
    • Appendicitis: While less common, appendicitis can present with vomiting, especially if the appendix ruptures, leading to peritonitis, a life-threatening condition.
    • Intestinal obstruction: This is a serious condition where the intestine is blocked, which can lead to severe vomiting, constipation, and abdominal pain.
    • Pancreatitis: Inflammation of the pancreas can cause severe abdominal pain and vomiting, and if not treated promptly, can lead to serious complications.
    • Meningitis: Although less directly associated with vomiting, in severe cases, especially in children, meningitis can present with vomiting along with fever, headache, and stiff neck.
  • Rare diagnoses:
    • Brain tumors: Certain brain tumors, especially those in the posterior fossa or cerebellum, can cause vomiting due to increased intracranial pressure.
    • Increased intracranial pressure (ICP): Conditions that increase pressure inside the skull, such as a subdural hematoma or cerebral edema, can lead to vomiting.
    • Porphyrias: A group of rare genetic disorders that can cause a variety of symptoms, including severe abdominal pain, vomiting, and neurological symptoms.
    • Cyclic vomiting syndrome: A rare condition characterized by recurring episodes of severe vomiting, often without an identifiable cause.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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