Can a patient with a pacemaker (pacemaker) receive a Nexplanon (etonogestrel implant) insertion in their arm?

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Last updated: October 29, 2025View editorial policy

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Nexplanon Insertion in Patients with Pacemakers

Yes, Nexplanon can be safely inserted in the arm of a patient with a cardiac pacemaker, as there are no contraindications or interactions between the two devices. 1

Rationale for Safety

  • Cardiac pacemakers are implanted in the chest area, while Nexplanon is inserted subcutaneously in the upper arm, creating adequate anatomical separation between the devices 1, 2
  • The European Society of Cardiology/European Society of Anaesthesiology guidelines specifically address perioperative management of patients with pacemakers, with no contraindications for subcutaneous implants in other body areas 1
  • Nexplanon exerts its contraceptive effects primarily through hormonal mechanisms (suppression of ovulation) and does not emit electromagnetic interference that could affect pacemaker function 3

Important Considerations for Insertion

  • The healthcare provider should document the presence of the pacemaker in the patient's chart before Nexplanon insertion 1
  • Standard Nexplanon insertion technique should be followed, with particular attention to:
    • Proper subdermal placement in the inner aspect of the non-dominant upper arm 3, 4
    • Avoiding deep insertion that might affect nearby neurovascular structures 4
    • Using the redesigned Nexplanon applicator that increases insertion accuracy 4

Potential Concerns and Mitigations

  • Electromagnetic interference: The Nexplanon insertion procedure does not involve electrocautery or other equipment that could interfere with pacemaker function 1, 5
  • Infection risk: While infection is a potential complication of any implant procedure, the risk is low (approximately 1.1-1.4%) and can be minimized with proper sterile technique 2
  • Anatomical considerations: The standard Nexplanon insertion site in the upper arm is anatomically distant from the pacemaker implantation site in the chest, eliminating concerns about device interaction 5

Alternative Insertion Sites

  • In rare cases where the standard insertion site might be problematic, alternative insertion sites such as the scapular region have been documented as safe and effective 6
  • However, for most patients with pacemakers, the standard upper arm insertion site remains appropriate 3

Follow-up Recommendations

  • Standard follow-up for both the pacemaker and Nexplanon should be maintained independently 5
  • Patients should be advised that Nexplanon does not affect pacemaker function and vice versa 1
  • Nexplanon should be removed or replaced after three years of use, as per standard recommendations 3

In conclusion, having a cardiac pacemaker does not contraindicate the use of Nexplanon, and the standard insertion technique in the upper arm remains appropriate for these patients 1, 3.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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