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Last updated: October 29, 2025View editorial policy

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Differential Diagnosis for Testicular Bleeding

  • Single most likely diagnosis
    • Testicular torsion: This is the most likely diagnosis because testicular torsion is a medical emergency that can cause severe pain and bleeding due to the twisting of the spermatic cord, cutting off the blood supply to the testicle.
  • Other Likely diagnoses
    • Testicular trauma: Direct injury to the testicles can cause bleeding, and this is a common scenario in cases of testicular bleeding.
    • Epididymitis: Inflammation of the epididymis, usually due to infection, can cause pain and potentially bleeding in the testicular area.
    • Varicocele: Enlargement of the veins within the scrotum can sometimes cause bleeding, although this is less common.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Testicular cancer with hemorrhage: Although rare, testicular cancer can cause bleeding, and missing this diagnosis could have severe consequences.
    • Spermatic cord thrombosis: A blood clot in the spermatic cord can cause testicular ischemia and potentially bleeding, which is a serious condition.
  • Rare diagnoses
    • Henoch-Schönlein purpura (HSP): A systemic vasculitis that can cause testicular pain and bleeding, although this is an uncommon presentation.
    • Polyarteritis nodosa (PAN): A rare autoimmune disorder that can affect various arteries, including those supplying the testicles, potentially leading to bleeding.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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