What ICD10 codes cover a baseline electrocardiogram (ECG) prior to starting phentermine (generic name: phentermine)

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 29, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

ICD-10 Codes for Baseline ECG Prior to Starting Phentermine

The appropriate ICD-10 code for a baseline ECG prior to starting phentermine is Z79.899 (Other long term (current) drug therapy) combined with Z13.6 (Encounter for screening for cardiovascular disorders). 1, 2

Rationale for Baseline ECG Before Phentermine Therapy

  • Phentermine is a sympathomimetic amine that can affect cardiovascular function by increasing norepinephrine levels in the central nervous system 1
  • Clinical guidelines recommend monitoring blood pressure and heart rate periodically during phentermine treatment 3
  • Phentermine is contraindicated in patients with a history of cardiovascular disease and uncontrolled hypertension 3, 1
  • A baseline ECG is important to rule out pre-existing cardiovascular conditions that would contraindicate phentermine use 1, 2

Appropriate ICD-10 Coding Strategy

Primary Codes

  • Z79.899 (Other long term (current) drug therapy) - This code indicates the ECG is being performed in relation to medication management 4
  • Z13.6 (Encounter for screening for cardiovascular disorders) - This code indicates the preventive screening nature of the ECG 5

Secondary Codes (if applicable)

  • E66.9 (Obesity, unspecified) - If the patient has obesity as the indication for phentermine 3
  • E66.01 (Morbid (severe) obesity due to excess calories) - For patients with BMI ≥40 kg/m² 3
  • E66.3 (Overweight) - For patients with BMI 25-29.9 kg/m² 3

Clinical Context for ECG Monitoring with Phentermine

  • The American Gastroenterological Association (AGA) guidelines state that "phentermine should be avoided in patients with a history of cardiovascular disease" 3
  • Implementation considerations in guidelines specify that "blood pressure and heart rate should be monitored periodically while taking phentermine" 3
  • Phentermine can potentially cause cardiovascular effects including:
    • Elevated blood pressure 1
    • Increased heart rate 1
    • Palpitations 3
    • Tachycardia 3

Best Practices for Documentation

  • Clearly document that the ECG is being performed as a baseline assessment prior to initiating phentermine therapy 3
  • Include the patient's BMI and weight-related complications in the documentation to support medical necessity 3
  • Document any cardiovascular risk factors that require monitoring during phentermine treatment 1, 2
  • If the patient has any pre-existing cardiovascular conditions, these should be coded separately 3

Coding Pitfalls to Avoid

  • Do not use Z01.810 (Encounter for preprocedural cardiovascular examination) as this is specifically for pre-surgical evaluations 5
  • Avoid using symptom codes (such as R00.0 for tachycardia) if the patient is not actually experiencing these symptoms 6
  • Do not use therapeutic drug monitoring codes (Z51.81) as phentermine levels are not typically monitored 4

References

Guideline

Cardiac Effects of Phentermine

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Phentermine's Cardiovascular Effects

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.