What are the guidelines for toenail wedge resection with application of phenol to the nail bed?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 29, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Toenail Wedge Resection with Phenol Application Guidelines

Phenol application for 45 seconds during wedge resection is the most effective treatment for ingrown toenails, with recurrence rates as low as 1.87% at 6 months compared to 73% with simple avulsion alone. 1, 2

Procedure Technique

  • Administer local anesthesia before the procedure for pain control 3
  • Create a bloodless field using a tourniquet at the base of the toe 2
  • Perform a partial nail avulsion (wedge resection) of the affected portion of the nail 2, 4
  • Apply 80% fresh phenol to the exposed nail matrix for 45 seconds to chemically ablate the nail-forming cells 2, 1
  • Clean the area thoroughly after phenol application to remove excess chemical 2

Indications

  • Ingrown toenails (onychocryptosis) with pain, inflammation, or infection 2, 5
  • Recurrent ingrown toenails after previous simple avulsion 2
  • Cases with hypertrophy of nail folds causing nail ingrowth 5

Advantages of Phenol Application

  • Low recurrence rate of 2.2-4.5% compared to 73% with simple avulsion alone 2, 4
  • Minimal postoperative discomfort and quick return to normal activities 5
  • Simple, inexpensive procedure that can be performed in general practice settings 2
  • Lower rates of post-operative infection and spike formation compared to wedge resection alone 4

Post-Procedure Management

  • Daily antiseptic soaks with dilute vinegar (50:50 dilution) or 2% povidone-iodine for 10-15 minutes twice daily 6
  • Apply mid to high-potency topical steroid ointment to nail folds twice daily to reduce inflammation 6
  • If infection is suspected, obtain cultures and initiate appropriate antibiotics with coverage against Staphylococcus aureus 3, 6
  • Regular nail trimming is necessary until the nail plate grows reattached 3
  • Monitor for signs of infection including increased pain, redness, swelling, or purulent drainage 3, 6

Management of Complications

  • For granulation tissue formation, options include scoop shave removal with hyfrecation or silver nitrate application 3, 6
  • For recurrence after phenolization (rare at 1.87-4.5%), repeat phenol cauterization is typically successful 2, 1
  • For persistent pain or drainage beyond 2-4 weeks, reassessment and possibly additional intervention may be required 6

Prevention of Recurrence

  • Ensure proper nail trimming technique - cut straight across, not too short 6
  • Wear comfortable well-fitting shoes and cotton socks 6
  • Avoid cutting cuticles or manipulating the nail folds 6
  • Apply topical emollients to cuticles and periungual tissues daily 6

Special Considerations

  • The medial nail fold has a higher recurrence rate than the lateral nail fold after phenolization 1
  • Patients with previous failed surgeries have higher recurrence rates (two-thirds of recurrences occur in patients with previous surgical failures) 2
  • Total nail ablation is rarely necessary; partial phenolization is usually sufficient 7
  • Early intervention is recommended to prevent complications and improve outcomes 7

References

Research

Evaluation of the Recurrence Rate of Ingrown Toenail After a 45-Second Matrix Cauterization With Phenol.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2024

Guideline

Nail Avulsion Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Best way to treat an ingrown toenail.

Dermatologic clinics, 2015

Guideline

Medical Management of Ingrown Nails

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.