What is the diagnosis and treatment plan for a 46-year-old male with acute lower back pain, exacerbated by prolonged standing, sitting, and bending, with a past medical history of prediabetes (pre-diabetes mellitus) and hyperlipidemia (elevated lipid levels), who has tried over-the-counter (OTC) Salonpas (methyl salicylate) patches and Ibuprofen (ibuprofen) 800 milligrams (mg) twice daily (BID) with mild to moderate relief?

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Differential Diagnosis

  • Single most likely diagnosis
    • Musculoskeletal strain: The patient's symptoms of diffuse lower back pain after heavy lifting, alleviated by OTC pain patches and ibuprofen, and worsened by prolonged standing, sitting, or bending, are consistent with a musculoskeletal strain. The absence of red flag symptoms such as fever, chills, or neurological deficits further supports this diagnosis.
  • Other Likely diagnoses
    • Lumbar degenerative disc disease: The patient's age and history of heavy lifting may contribute to degenerative changes in the lumbar spine, which could cause chronic lower back pain.
    • Lumbar facet joint pain: The patient's pain with flexion, extension, rotation, and lateral bending may indicate facet joint involvement, which is a common cause of lower back pain.
    • Paraspinal muscle spasm: The patient's mild tenderness to the lumbosacral region and pain with movement may indicate paraspinal muscle spasm, which can occur in response to injury or strain.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Cauda equina syndrome: Although the patient denies neurological symptoms such as saddle anesthesia, urinary retention, or leg weakness, cauda equina syndrome is a medical emergency that requires prompt recognition and treatment.
    • Spinal infection (e.g., osteomyelitis, discitis): The patient's mild pain and lack of systemic symptoms make this diagnosis less likely, but it is essential to consider spinal infection in patients with new-onset back pain, especially if they have risk factors such as diabetes or immunocompromised status.
    • Spinal fracture: Although the patient denies previous trauma, a spinal fracture could occur with minimal trauma in patients with osteoporosis or other underlying conditions.
  • Rare diagnoses
    • Ankylosing spondylitis: This chronic inflammatory disease can cause lower back pain and stiffness, but it is relatively rare and typically presents with additional symptoms such as morning stiffness and improvement with exercise.
    • Spinal tumor: Although rare, spinal tumors can cause back pain and neurological symptoms, and it is essential to consider this diagnosis in patients with unexplained or persistent back pain.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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