From the Research
The standard adult dose of Buscopan (hyoscine butylbromide) is 10-20 mg taken orally up to four times daily, with a maximum daily dose of 80 mg. This dosing recommendation is based on the most recent and highest quality study available, which provides guidance on the use of Buscopan for treating abdominal cramps and spasms 1.
Key Considerations
- For children aged 6-12 years, the recommended dose is 10 mg three times daily.
- Buscopan should be taken 20 minutes before meals for optimal effect in treating abdominal cramps and spasms.
- The medication works by relaxing smooth muscle in the gastrointestinal tract, reducing painful contractions and spasms.
- Injectable forms are available for more severe cases, typically administered at 20 mg doses.
- Side effects may include dry mouth, blurred vision, and constipation.
- Patients with glaucoma, enlarged prostate, myasthenia gravis, or intestinal obstruction should avoid Buscopan, as noted in various studies 2, 1, 3.
- The medication typically begins working within 15-30 minutes and its effects last for several hours.
Important Precautions
- Always follow your healthcare provider's specific dosing instructions as they may vary based on your condition and medical history.
- Buscopan should be used with caution in patients with cardiac comorbidities, as it may have adverse effects on heart rate and rhythm 1.
- In cases where Buscopan has been used, patients should be counselled postprocedurally and told to present to an emergency facility should they experience eye pain, redness, decreased vision, nausea and vomiting or headache.
Evidence Summary
The evidence from various studies 2, 1, 4 supports the use of Buscopan for treating abdominal cramps and spasms, with a focus on its anticholinergic properties and smooth muscle relaxation effects. However, the most recent and highest quality study 1 provides the most relevant guidance on dosing and precautions.