Treatment of Esophageal Rings
For symptomatic Schatzki's rings, offer a single dilatation session using graded dilatation to a relatively large diameter (16-20 mm) followed by proton pump inhibitor therapy to reduce risk of relapse. 1, 2
Diagnosis and Classification
- Schatzki's ring is an annular constriction at the gastroesophageal mucosal junction, covered proximally by squamous epithelium and distally by gastric mucosa 2
- Occurs in 6-14% of barium swallow examinations and is often asymptomatic 2
- "Schatzki's rule" states that dysphagia is usual with ring diameters ≤13 mm, rarely occurs if diameter exceeds 20 mm, with a "grey area" between 13-20 mm where symptoms are less consistently observed 2
- Consider excluding eosinophilic esophagitis by obtaining distal, mid and proximal esophageal biopsies in symptomatic patients 1, 2
Treatment Algorithm
First-line Treatment
- For symptomatic patients, perform a single dilatation session using graded dilatation to a relatively large diameter (16-20 mm) 1, 2
- Dilatation therapy is directed toward achieving rupture of the ring, therefore larger calibre dilators may be needed 2
- Do not offer dilatation for asymptomatic Schatzki's rings incidentally discovered on diagnostic endoscopy or contrast studies 1
- Prescribe PPI therapy after dilatation, as this significantly reduces the risk of relapse 1, 2
Alternative Treatment Options
- Electrosurgical incision is an effective alternative treatment to esophageal dilatation for relieving dysphagia related to Schatzki's ring 1, 3
- Some patients with dysphagia due to Schatzki's ring may be relieved by PPI therapy alone without the need for dilatation 2, 4
- Complete Schatzki ring obliteration with jumbo cold biopsy forceps has been shown to be safe and effective in small studies 5
Evidence for GERD Association and PPI Therapy
- Gastroesophageal reflux disease (GERD) is implicated in the pathogenesis of Schatzki's rings 6
- PPI therapy after dilatation significantly reduces the risk of relapse compared with placebo at up to 48 months of follow-up 2
- Offer PPI therapy rather than H2 receptor antagonists, which are ineffective in reducing the need for repeat dilatation 1
- A study demonstrated significant improvements in both ring lumen diameter and ability to pass a tablet through the esophagus with acid suppression medication alone 4
Complications and Follow-up
- Perforation is a potential risk with any esophageal dilatation procedure, though the risk is lower with Schatzki rings compared to other esophageal strictures 2
- Consider performing a water-soluble contrast swallow after dilatation to screen for perforation, though this is not essential 1
- Recurrence is common after traditional dilatation methods, requiring repeat procedures 3
- Long-term PPI therapy significantly reduces the risk of relapse 2