What causes constipation in a neonate?

From the Research

Causes of Constipation in Neonates

• Constipation that is present from birth or that begins in the neonatal period is most likely to be congenital in origin 1
• Hirschsprung's disease, a congenital cause of severe constipation, occurs in one of every 5,000 births and can cause constipation in neonates 2, 1
• Delayed passage of meconium beyond 48 hours of life is a red flag for constipation in neonates 3

Functional vs. Organic Causes

• Functional constipation is the most common type of constipation, accounting for 90-95% of all cases 4
• Organic causes of constipation, such as Hirschsprung's disease, are less common but can be identified through a thorough history and physical examination 2, 1, 4

Diagnosis and Evaluation

• A detailed history and targeted physical examination can rule out most organic causes of chronic constipation 3
• Laboratory investigations are usually not necessary in patients with mild constipation, but may be warranted in cases of suspected organic disease 1, 4