Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 30, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Eye Problem and On-and-Off Fever

Single Most Likely Diagnosis

  • Conjunctivitis: This is a common condition that can cause eye problems such as redness, itching, and discharge, and can be associated with on-and-off fever, especially if it's caused by a viral or bacterial infection.

Other Likely Diagnoses

  • Uveitis: This inflammation of the uvea can cause eye pain, sensitivity to light, and vision problems, and may be accompanied by fever if it's due to an infectious cause.
  • Orbital Cellulitis: An infection of the tissues surrounding the eye, which can cause eye pain, swelling, and fever.
  • Keratitis: An infection of the cornea that can cause eye pain, redness, and vision problems, and may be associated with fever.

Do Not Miss Diagnoses

  • Endophthalmitis: A severe infection within the eye that can cause vision loss and is a medical emergency. Fever may be present, and prompt treatment is necessary.
  • Meningitis: Although less directly related to eye problems, meningitis can cause fever and, in some cases, eye symptoms such as photophobia. It's a life-threatening condition that requires immediate medical attention.
  • Syphilis: In its secondary stage, syphilis can cause a wide range of symptoms including fever and eye problems like uveitis or conjunctivitis. It's crucial to consider this diagnosis due to its potential for serious complications if left untreated.

Rare Diagnoses

  • Toxocariasis: A parasitic infection that can cause ocular larva migrans, leading to eye problems. It's more common in children and can be associated with fever.
  • Cysticercosis: Caused by the pork tapeworm, this condition can lead to eye problems if the larvae infect the eye. Fever may be present, especially during the initial infection phase.
  • Ocular Lyme Disease: Lyme disease can cause various eye problems, including conjunctivitis and uveitis, and is associated with fever in its early stages. It's rare but should be considered in endemic areas.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.