What are the key points for third trimester prenatal care?

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Last updated: March 27, 2025View editorial policy

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From the Guidelines

Third trimester care should prioritize monitoring maternal and fetal health, preparing for delivery, and addressing common concerns, with prenatal visits every 2-3 weeks until 36 weeks, then weekly until delivery, as recommended by recent guidelines 1. The key points for third trimester prenatal care include:

  • Monitoring maternal blood pressure, as hypertension risk increases during this period
  • Measuring fundal height to assess fetal growth
  • Determining fetal position to prepare for delivery
  • Conducting fetal heart rate checks to ensure fetal well-being
  • Routine screening for Group B Streptococcus at 35-37 weeks, with treatment using intravenous penicillin G if positive 1
  • Daily monitoring of fetal movements, with immediate reporting of decreased activity
  • Tdap vaccination between 27-36 weeks to provide passive immunity to the newborn Common third trimester concerns that should be addressed include:
  • Heartburn, treated with lifestyle modifications and antacids
  • Lower back pain, managed with proper body mechanics and support
  • Leg cramps, improved with hydration and stretching
  • Sleep disturbances, which can be mitigated with relaxation techniques and sleep hygiene practices Women should be aware of warning signs that require immediate attention, such as:
  • Vaginal bleeding
  • Severe headaches
  • Visual changes
  • Sudden swelling
  • Contractions before 37 weeks
  • Rupture of membranes
  • Decreased fetal movement Birth planning, including delivery preferences and pain management options, should be discussed with healthcare providers during this period to ensure a safe delivery, with consideration of the most recent guidelines and evidence-based practices 1.

From the Research

Key Points for Third Trimester Prenatal Care

  • Screening for gestational diabetes between 24 and 28 weeks is recommended for all patients 2, 3
  • Testing for group B Streptococcus should be performed between 36 and 37 weeks, and intrapartum antibiotic prophylaxis should be initiated to decrease the risk of neonatal infection 2
  • People at risk of preeclampsia, including those diagnosed with COVID-19 in pregnancy, should be offered 81 mg of aspirin daily starting at 12 weeks 2
  • Routine immunizations for all pregnant women include influenza vaccine; tetanus toxoid, reduced diphtheria, acellular pertussis (Tdap) vaccine 2, 3
  • Women with risk factors should be screened in the first trimester for gestational diabetes mellitus 3
  • Induction of labor may be offered to women with chronic medical conditions before 41 weeks, based on the condition and relative risks and benefits of continued pregnancy 3
  • Women without maternal or fetal indications should not be offered elective delivery before 39 weeks, but should be offered induction at 41 weeks with a recommendation for delivery before 42 weeks 3
  • Routine third-trimester ultrasonography does not reduce adverse perinatal outcomes in low-risk pregnancies 4
  • Third-trimester repeat HIV testing is recommended for individuals known to be at high risk of acquiring HIV, but some studies suggest that universal third-trimester repeat HIV testing may be beneficial in reducing perinatal transmission 5
  • Prenatal yoga exercises may improve sleep quality in third-trimester pregnant women 6

Additional Recommendations

  • Identification and treatment of periodontal disease decreases preterm delivery risk 2
  • Treatment of iron deficiency anemia decreases the risk of preterm delivery, intrauterine growth restriction, and perinatal depression 2
  • Ancestry-based genetic risk stratification using family history can inform genetic screening 2
  • Folic acid supplementation (400 to 800 mcg daily) decreases the risk of neural tube defects 2
  • All pregnant patients should be screened for asymptomatic bacteriuria, sexually transmitted infections, and immunity against rubella and varicella 2
  • Universal screening for depression, anxiety, intimate partner violence, substance use, and food insecurity is recommended early in pregnancy 2

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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