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Last updated: October 30, 2025View editorial policy

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Differential Diagnosis for Patient with Endinomyosis and Urinary Difficulty

  • Single most likely diagnosis:
    • Ureteral obstruction due to endometriosis: This is a common complication of endometriosis, where the growths can cause blockage of the ureters, leading to difficulty in passing urine and pain.
  • Other Likely diagnoses:
    • Pelvic floor dysfunction: Endometriosis can cause chronic pain and inflammation, leading to pelvic floor muscle spasms and dysfunction, which can cause urinary difficulty.
    • Constipation: Chronic pain and inflammation from endometriosis can also cause constipation, which can put pressure on the urethra and bladder, leading to urinary difficulty.
    • Interstitial cystitis: This is a condition that causes bladder pain and urinary frequency, which can be exacerbated by endometriosis.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.):
    • Ureteral rupture: Although rare, ureteral rupture due to obstruction from endometriosis can be life-threatening and requires immediate medical attention.
    • Kidney damage: Prolonged ureteral obstruction can cause kidney damage, which can lead to chronic kidney disease or even kidney failure.
    • Malignant transformation: Although rare, endometriosis can undergo malignant transformation, which can cause urinary difficulty and other symptoms.
  • Rare diagnoses:
    • Neurogenic bladder: This is a condition where the nerves that control the bladder are damaged, leading to urinary difficulty and other symptoms.
    • Fowler's syndrome: This is a rare condition that causes urinary retention due to a functional obstruction of the urethra.
    • Urethral stricture: This is a rare condition where the urethra is narrowed, causing urinary difficulty and other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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