How should I manage a new or worsening symptom?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 30, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Management of New or Worsening Symptoms

When experiencing a new or worsening symptom, you should seek immediate medical attention if symptoms are severe, persistent, or concerning, as this could indicate a serious condition requiring prompt evaluation and treatment. 1, 2

General Approach to New or Worsening Symptoms

  • For any new or worsening symptom, the first step is to assess the severity and potential urgency of the situation 2
  • If symptoms are severe (significant pain, difficulty breathing, changes in consciousness), call emergency services (9-1-1) immediately 2
  • For symptoms that are mild but worsening, contact your healthcare provider promptly for guidance 2

Specific Guidance Based on Symptom Type

Chest Pain or Discomfort

  • If you experience chest pain or discomfort and have previously been prescribed nitroglycerin:
    • Take 1 dose of nitroglycerin immediately 2
    • If symptoms are unimproved or worsen after 5 minutes, call 9-1-1 immediately 2
    • If symptoms improve significantly after one dose but don't completely resolve, you may repeat nitroglycerin every 5 minutes for a maximum of 3 doses, but call 9-1-1 if symptoms persist 2
  • If you experience chest pain or discomfort and have NOT been prescribed nitroglycerin:
    • Call 9-1-1 immediately if symptoms are unimproved or worsen after 5 minutes 2
    • If symptoms completely subside within 5 minutes, notify your physician about the episode 2

Respiratory Symptoms (Asthma)

  • For worsening asthma symptoms:
    • Use your rescue inhaler (SABA) as prescribed 2
    • If symptoms don't improve after using your rescue inhaler, seek immediate medical attention 2
    • For patients with a written asthma action plan, follow the instructions for worsening symptoms 2
  • High-risk patients (previous severe exacerbation, frequent ED visits, high SABA use) should seek medical care early during an exacerbation 2

Pain or Fever

  • For pain that worsens or lasts more than 10 days, stop over-the-counter medications and consult your doctor 1
  • For fever that worsens or lasts more than 3 days, seek medical evaluation 1
  • If redness or swelling develops with pain, this could indicate a serious condition requiring prompt medical attention 1

Sinus Symptoms

  • For persistent sinus symptoms after initial treatment:
    • Contact your healthcare provider as this may indicate bacterial sinusitis requiring antibiotic therapy 3
    • Monitor for warning signs like high fever, severe headache, or visual changes that could indicate complications 3

Rheumatic and Musculoskeletal Disease Symptoms

  • Patients with rheumatic and musculoskeletal diseases who experience worsening of COVID-19 symptoms should immediately seek healthcare advice from an expert in treating COVID-19 2
  • For new or worsening symptoms in patients with rheumatic conditions, contact your rheumatologist for guidance on medication adjustments 2

Neurological or Motor Symptoms

  • For regression of motor skills, loss of strength, or concerns with respiration or swallowing, seek urgent reevaluation 2
  • Progressive disorders must be brought to medical attention immediately 2

When to Seek Emergency Care

  • Call 9-1-1 or seek immediate emergency care if you experience:
    • Severe chest pain or pressure, especially if accompanied by shortness of breath, sweating, or nausea 2
    • Sudden severe headache or changes in vision 3
    • Difficulty breathing or shortness of breath 2
    • Sudden weakness, numbness, or inability to speak 2
    • High fever with severe symptoms 1

When to Contact Your Healthcare Provider

  • Contact your healthcare provider for:
    • Symptoms that persist or worsen despite initial treatment 3
    • New symptoms that develop during treatment 1
    • Pain that lasts more than 10 days or fever that lasts more than 3 days 1
    • Worsening of chronic condition symptoms 2
    • Changes in medication effectiveness 2

Follow-up Care

  • For chronic conditions, regular follow-up visits (e.g., annual) with your healthcare provider are recommended to evaluate disease status and assess changes that may require intervention 2
  • After experiencing new or worsening symptoms, follow up with your provider if symptoms don't improve within the expected timeframe 3
  • Consider further evaluation of underlying risk factors if symptoms recur frequently 3

Remember that early recognition and response to worsening symptoms can significantly reduce morbidity and mortality from serious conditions 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Acute Sinusitis with Persistent Symptoms After Initial Treatment

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.