What is the diagnosis of a persistent painful arm lump?

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Differential Diagnosis for a Lump on the Arm Hurting for 5 Months

Single Most Likely Diagnosis

  • Lipoma: A benign tumor composed of fat tissue, which is common and can cause a lump that may be painful if it presses on nearby nerves or has grown large enough to cause discomfort.

Other Likely Diagnoses

  • Cyst: Such as an epidermoid cyst or sebaceous cyst, which can become inflamed and painful.
  • Abscess: A collection of pus that has built up within the tissue of the arm, often caused by a bacterial infection, which can be painful and form a lump.
  • Hematoma: A collection of blood outside of blood cells, which can occur after an injury and may cause a painful lump.
  • Infected or inflamed lymph node: Can cause a painful lump in the arm, especially if there's an underlying infection.

Do Not Miss Diagnoses

  • Soft tissue sarcoma: Although rare, this is a type of cancer that originates in the soft tissues (such as muscles, fat, blood vessels, and tendons) and can present as a painful lump. Early detection is crucial.
  • Metastatic tumor: A tumor that has spread from another part of the body to the arm, which could present as a lump and may be painful.
  • Osteosarcoma: A type of bone cancer that could cause a lump and pain in the arm if the tumor is located near the surface of the bone.

Rare Diagnoses

  • Neurofibroma: A benign tumor of the nerve tissue, which can cause a lump and may be painful if it presses on the nerve.
  • Giant cell tumor: A rare, benign tumor that typically occurs in the bone but can extend into the soft tissue, causing a lump.
  • Myositis ossificans: A condition where there is heterotopic ossification of soft tissue (usually muscle), which can form a painful lump after trauma.
  • Pilomatrixoma: A rare, benign skin tumor that originates from the hair follicle matrix and can cause a lump, sometimes painful.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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