Differential Diagnosis for Irritated Skin around Eyes

• Single most likely diagnosis
  • Allergic conjunctivitis: This is a common condition characterized by an immune response to allergens such as pollen, dust, or pet dander, leading to irritation, redness, and itching around the eyes.
• Other Likely diagnoses
  • Dry eye syndrome: Inadequate tear production or poor tear quality can cause irritation, itchiness, and redness around the eyes.
  • Eczema (atopic dermatitis): A chronic skin condition that can cause dry, itchy, and inflamed skin, including around the eyes.
  • Contact dermatitis: An allergic or irritant reaction to substances like makeup, soap, or skincare products can cause skin irritation around the eyes.
  • Blepharitis: Inflammation of the eyelids can cause redness, itching, and irritation due to bacterial or demodex mite infestations.
• Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
  • Orbital cellulitis: A bacterial infection of the tissues surrounding the eye, which can lead to serious complications if not promptly treated.
  • Herpes zoster (shingles): A viral infection that can cause a painful rash around the eyes and potentially lead to complications like vision loss if not treated.
  • Angioedema: A severe allergic reaction that can cause rapid swelling of the skin and mucous membranes, potentially leading to airway obstruction.
• Rare diagnoses
  • Sjögren's syndrome: An autoimmune disorder that can cause dry eyes and skin irritation, among other symptoms.
  • Sarcoidosis: A condition characterized by the growth of granulomas in various parts of the body, including the skin around the eyes.
  • Trachoma: A bacterial infection that can cause chronic eye inflammation and scarring, leading to vision loss if left untreated.