From the Research
Dosing of Oxcarbazepine for Trigeminal Neuralgia
- The mean maintenance dose of oxcarbazepine in patients with trigeminal neuralgia was 773.7 mg/day, as reported in a study published in 2008 1.
- Another study from 1989 found that the daily effective dose range of oxcarbazepine for trigeminal neuralgia was 1200-2400 mg, corresponding to a serum therapeutic concentration range of 50-110 mumol/l of 10-OH-carbazepine 2.
- A retrospective study from 2014 reported a median dose of 1200 mg (range 600-1800) of oxcarbazepine for patients with classical trigeminal neuralgia 3.
- A review article from 2024 discussed the use of oxcarbazepine for trigeminal neuralgia, but did not provide specific dosing information 4.
- A real-world study from 2021 reported that oxcarbazepine was effective in 90.9% of patients with trigeminal neuralgia, but did not provide detailed dosing information 5.
Effective Dose Range
- The effective dose range of oxcarbazepine for trigeminal neuralgia is generally considered to be between 600-1800 mg/day, based on the available evidence 1, 2, 3.
- The optimal dose of oxcarbazepine for individual patients may vary, and should be determined based on clinical response and tolerability 1, 2, 3.