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Differential Diagnosis for Friable Cervical Mass

Single Most Likely Diagnosis

  • Cervical cancer: This is the most likely diagnosis due to the description of the mass as friable, which suggests a tumor that is likely to bleed easily, a characteristic often associated with malignant neoplasms, particularly in the context of cervical cancer.

Other Likely Diagnoses

  • Cervical polyp: Although less likely than cancer, a polyp could present as a friable mass, especially if it becomes necrotic or infected.
  • Cervicitis: Inflammation of the cervix could lead to a friable appearance, especially if there is significant ulceration or infection.
  • Metastatic disease: Other cancers can metastasize to the cervix, presenting as a friable mass, though this is less common.

Do Not Miss Diagnoses

  • Invasive placental tissue (e.g., placenta accreta) in pregnancy: Although rare, this condition can present with a friable cervical mass and is critical to diagnose due to its potential for severe bleeding and complications in pregnancy.
  • Gestational trophoblastic disease: This includes conditions like choriocarcinoma, which can present with a friable mass and has significant implications for both mother and fetus if not promptly diagnosed and treated.

Rare Diagnoses

  • Cervical lymphoma: Primary lymphoma of the cervix is rare but can present as a friable mass.
  • Cervical melanoma: Although extremely rare, melanoma can occur in the cervix and may present as a friable, pigmented mass.
  • Carcinosarcoma: A rare malignant tumor that contains both carcinoma and sarcoma elements, which could present as a friable cervical mass.
  • Leiomyosarcoma: A rare smooth muscle tumor that could present in the cervix, though more commonly found in the uterus.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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