Recommended Dose of Augmentin for a 23 kg Child
For a 23 kg child, the recommended dose of Augmentin (amoxicillin-clavulanate) is 45 mg/kg/day in two divided doses. 1
Dosing Details
- For a child weighing 23 kg, the appropriate dosage falls in the weight category of >15-23 kg, which corresponds to 45 mg twice daily of the amoxicillin component 1
- The FDA-approved dosing for Augmentin in children is based on weight categories, with specific recommendations for children weighing >15-23 kg 1
- The total daily dose should be divided into two equal doses given every 12 hours for optimal therapeutic effect 1
Administration Considerations
- Augmentin should be taken at the start of a meal to minimize potential gastrointestinal intolerance 1
- The oral suspension should be shaken well before using and can be administered directly or mixed with formula, milk, fruit juice, or water 1
- Any unused portion of the reconstituted suspension must be discarded after 14 days 1
Treatment Duration
- Treatment should be continued for a minimum of 48 to 72 hours beyond the time that the patient becomes asymptomatic 1
- For infections caused by Streptococcus pyogenes, a minimum of 10 days of treatment is recommended to prevent acute rheumatic fever 1
- Some infections may require several weeks of therapy with clinical and/or bacteriological follow-up for several months after treatment 1
Common Pitfalls to Avoid
- Avoid underdosing, which can lead to treatment failure and promote antimicrobial resistance 1
- Do not continue therapy longer than necessary, as this increases the risk of side effects and antimicrobial resistance 1
- Remember that refrigeration of the reconstituted suspension is preferable but not required 1
Special Considerations
- For children with renal impairment, dose adjustments may be necessary if the glomerular filtration rate is less than 30 mL/min 1
- For persistent or recurrent acute otitis media with risk factors for drug-resistant pathogens, higher doses may be considered 2
- Limiting the duration of antimicrobial therapy to the shortest effective course will minimize selection for resistance 1